Chlorprothixene EP Impurity E CAS 86-39-5
| CAS No. | 86-39-5 |
| Molecular Formula | C13H7ClOS |
| Molecular Weight | 246.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Chlorprothixene EP Impurity E (CAS 86-39-5), a pharmacopoeial impurity reference standard (molecular formula C13H7ClOS, MW 246.71 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H7ClOS, Chlorprothixene EP Impurity E contains sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 246.71 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H7ClOS |
| Molecular Weight | 246.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorprothixene Standards
- Chlorprothixene Hydrochloride - Impurity B (CAS 2622-24-4)
- Chlorprothixene EP Impurity F (CAS 4546-35-4)
- Chlorprothixene (CAS 113-59-7)
- Chlorprothixene EP Impurity A (CAS 4295-65-2)
- Chlorprothixene EP Impurity F HCl (CAS 2461-06-5；4546-35-4 (free base))
- Chlorprothixene EP Impurity B HCl (CAS 4907-84-0)
- Chlorprothixene EP Impurity C HCI (CAS 51382-91-3 (free base))
- Chlorprothixene hydrochloride (CAS 6469-93-8)
Recommended Standards
- Ethyl 4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carboxylate (CAS 583878-42-6)
- Pitolisant impurity 14 (CAS CATO-C4X-252014)
- Ethyl 4-chloro-2-(ethylthio)pyrimidine-5-carboxylate (CAS 2223-96-3)
- Haloperidol Impurity N16 (CAS 57390-39-3)
- Dabigatran Impurity 74 (CAS 1610758-21-8)
- Lifitegrast Impurity 13 (CAS CATO-C4X-240913)
- Pregabalin impurity 99 (CAS 1511511-44-6)
- 3-bromo-4-fluoro-5-methylpyridine (CAS 1211536-44-5)
- tert-butyl ((4S,5S)-2,5-dimethyl-3-oxohept-1-en-4-yl)carbamate (CAS 1796585-39-1)
- N-((1R,3S,4S)-3-((4-(3-Benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)cyclopentyl)-N-methyl-D-valine (CAS 313994-79-5)
- 5-Bromo-6-(oxetan-3-yloxy)pyrimidin-4(3H)-one (CAS 1603077-97-9)
- tert-Butyl 5-nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate (CAS 1186638-24-3)
- Dotinurad Impurity 147 (CAS CATO-C4X-2494147)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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