4-(Bromomethyl)-5-(tert-butyl)-1,3-dioxol-2-one CAS 86005-12-1
| CAS No. | 86005-12-1 |
| Molecular Formula | C8H11BrO3 |
| Molecular Weight | 235.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(Bromomethyl)-5-(tert-butyl)-1,3-dioxol-2-one (CAS 86005-12-1), molecular formula C8H11BrO3 and molecular weight 235.08 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, 4-(Bromomethyl)-5-(tert-butyl)-1,3-dioxol-2-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-(Bromomethyl)-5-(tert-butyl)-1,3-dioxol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11BrO3 |
| Molecular Weight | 235.08 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Br-containing |
Related Bromomethyl Standards
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- 3-(Bromomethyl)-1,5,5-trimethylimidazolidine-2,4-dione (CAS 159135-61-2)
- 1-(Bromomethyl)-4-(1,1-difluoroethyl)benzene (CAS 1654773-79-1)
- Methyl 5-(bromomethyl)thiophene-2-carboxylate, 97% (CAS 108499-32-7)
- Methyl 5-(bromomethyl)thiophene-3-carboxylate (CAS 191934-27-7)
- 2-(5-(Bromomethyl)thiophen-2-yl)acetic acid (CAS 200418-14-0)
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Recommended Standards
- 4-(4-Bromophenyl)pyrimidine (CAS 53975-33-0)
- 4-Bromo-1-napthaldehyde (CAS 50672-84-9)
- 3-Bromo-6-methyl-1H-indole-5-carbonitrile (CAS 2102934-04-1)
- 4-Bromo-2,3'-bipyridine (CAS 62913-27-3)
- (R)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)but-3-en-1-amine (CAS 1272736-42-1)
- 3-Isobutyl-1,3-thiazolidine-2,4-dione (CAS 98431-78-8)
- 6-Bromo-3-nitropyrazolo[1,5-a]pyrimidine (CAS 300361-77-7)
- 2-(1H-Indol-2-yl)benzoic acid (CAS 4992-08-9)
- Methyl (2E)-3-(4-nitrophenyl)-2-phenylacrylate (CAS 42443-21-0)
- Methyl 2-chloro-4,6-difluorobenzoate (CAS 1261869-14-0)
- 2-Phenyl-5-(piperazin-1-yl)oxazole-4-carbonitrile hydrochloride (CAS 1226259-07-9)
- (S)-Benzyl ethyl((1-(2-hydroxyethyl)pyrrolidin-2-yl)methyl)carbamate (CAS 1354001-72-1)
- N-(2-((3-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)-2-(thiophen-2-yl)acetamide (CAS 1058249-85-6)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
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