4-Chloro-6-ethoxy-2-phenylquinoline CAS 860197-69-9
| CAS No. | 860197-69-9 |
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-6-ethoxy-2-phenylquinoline (CAS 860197-69-9) is a high-purity analytical reference standard with the molecular formula C17H14ClNO and a molecular weight of 283.75 g/mol.
4-Chloro-6-ethoxy-2-phenylquinoline (C17H14ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-6-ethoxy-2-phenylquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-ethoxy-3-phenylquinoline (CAS 1031928-18-3)
- 2-Chloro-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-N-isopropylacetamide (CAS 1175914-93-8)
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- (S)-2-(4-Chloro-benzoylamino)-3-methyl-butyric acid ethyl ester (CAS 1212407-66-3)
- Ethyl 2-[1-(6-Chloro-3-pyridazinyl)-4-piperidyl]acetate (CAS 1246471-48-6)
- 2-chloro-1-[2-(3,4-dimethoxyphenyl)pyrrolidin-1-yl]ethan-1-one (CAS 1306604-10-3)
- 1-[3-(6-Chloro-2-methyl-pyrimidin-4-yl)-piperidin-1-yl]-2-methoxy-ethanone (CAS 1316217-89-6)
- 1-[4-(6-Chloro-2-methyl-pyrimidin-4-yl)-piperidin-1-yl]-2-methoxy-ethanone (CAS 1316220-05-9)
Recommended Standards
- 4-Chloro-5-(cyclopropylamino)-2-(3,3-dimethyl-2-oxobutyl)pyridazin-3(2H)-one (CAS 477860-40-5)
- 4-Methyl-3-(n-methylsulfamoyl)benzenesulfonyl chloride (CAS 923697-69-2)
- 4-Chloro-5-(cyclohexylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one (CAS 477855-88-2)
- 5-Chloro-2-(1-naphthylmethoxy)aniline (CAS 946682-48-0)
- 3-(4-Bromo-1-methyl-1h-pyrrole-2-carboxamido)-2-methylpropanoic acid (CAS 1247061-71-7)
- 2-Chloro-4,6-dimethyl-3-phenylmethanesulfonylpyridine (CAS 866038-64-4)
- 3-Methyl-4-(pyridin-4-yloxy)aniline (CAS 871020-28-9)
- 8-(((2r,5r)-5-Amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1648863-90-4)
- 1-Boc-2,2-dimethylpyrrolidine (CAS 869527-80-0)
- Potassium 4-(2-oxobenzo[cd]indol-1(2H)-yl)butane-1-sulfonate (CAS 1151666-52-2)
- 2-(3-Aminophenoxy)-1-(azetidin-1-yl)ethan-1-one (CAS 1179724-69-6)
- 4-chloro-2-fluoro-pyridine-3-carbaldehyde (CAS 1232432-20-0)
- (S)-1-(2-fluoro-3-methylphenyl)ethan-1-amine (CAS 1213124-00-5)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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