Nafamostat Impurity 40 CAS 860363-16-2
| CAS No. | 860363-16-2 |
| Molecular Formula | C13H9NO2 |
| Molecular Weight | 211.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Nafamostat Impurity 40 (C13H9NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Nafamostat Impurity 40 (CAS 860363-16-2), a pharmacopoeial impurity reference standard (molecular formula C13H9NO2, MW 211.22 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9NO2 |
| Molecular Weight | 211.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Nafamostat Standards
- Nafamostat impurity 80 (CAS 2055540-27-5)
- Nafamostat Impurity 20 (CAS CATO-C4X-133220)
- Nafamostat Impurity 36 (CAS 765871-54-3)
- Nafamostat impurity 76 (CAS CATO-C4X-133276)
- Nafamostat Impurity 54 (CAS CATO-C4X-133254)
- Nafamostat impurity 96 (CAS CATO-C4X-133296)
- Nafamostat impurity 78 (CAS 66217-26-3)
- Nafamostat impurity 126 (CAS CATO-C4X-1332126)
Recommended Standards
- Milrinone Impurity 8 (CAS 106637-42-7)
- Brimonidine Impurity 23 (CAS CATO-C4X-156623)
- Milrinone Impurity 29 (CAS CATO-C4X-109129)
- Brimonidine Impurity 27 (CAS 185312-10-1)
- Palonosetron Impurity 37 (CAS CATO-C4X-110537)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
- Mivacurium chloride Impurity 28 (CAS 213999-55-4)
- N-(3-((8-Bromo-6-(dimethylamino)-9H-purin-9-yl)methyl)phenyl)formamide (CAS 123811-36-9)
- 2-(3-Bromophenyl)-5-((tert-butoxycarbonyl)amino)thiazole-4-carboxylic acid (CAS 1270034-29-1)
- 5-Chloro-2-fluoronicotinic acid ethyl ester (CAS 1214345-81-9)
- 5-Methyl-2-(2-methylphenoxy)aniline (CAS 946715-75-9)
- 1-[(4-Methoxyphenyl)methyl]-3-methyl-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 861206-01-1)
- tert-Nonyl Mercaptan (mixture) (CAS 55646-15-6)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com