5-(4-Fluorophenyl)-6-[2-(4-methylpiperazino)ethyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile CAS 860612-14-2
| CAS No. | 860612-14-2 |
| Molecular Formula | C20H21FN6 |
| Molecular Weight | 364.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(4-Fluorophenyl)-6-[2-(4-methylpiperazino)ethyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 860612-14-2) is a high-purity analytical reference standard with the molecular formula C20H21FN6 and a molecular weight of 364.42 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 5-(4-Fluorophenyl)-6-[2-(4-methylpiperazino)ethyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-(4-Fluorophenyl)-6-[2-(4-methylpiperazino)ethyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21FN6 |
| Molecular Weight | 364.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Fluorophenyl Standards
- 4-[4-(2-Fluorophenyl)piperazin-1-yl]-5-methoxy-2-phenylpyrimidine (CAS 477863-89-1)
- 3-(2-Fluorophenyl)-4-(((2-hydroxynaphthalen-1-yl)methylene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 676333-72-5)
- 3-(4-Fluorophenyl)-4-(((2-hydroxynaphthalen-1-yl)methylene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 577983-00-7)
- 1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-((4-fluorophenyl)thio)propan-2-ol (CAS 338421-88-8)
- 3-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)benzoic acid (CAS 438029-79-9)
- 5-(2-Fluorophenyl)-2-methylindeno[1,2-d]thiazolo[3,2-a]pyrimidine-3,6(2H,5H)-dione (CAS 860788-37-0)
- 6-(2-Fluorophenyl)-2,3-dihydro-4H-indeno[1',2':4,5]pyrimido[2,1-b][1,3]thiazine-4,7(6H)-dione (CAS 860788-38-1)
- N-(4-(4-Fluorophenyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)methanesulfonamide (CAS 945966-46-1)
Recommended Standards
- 4`-Hydroxy Torsemide (CAS 99300-67-1)
- bis(4-(dimethylamino)phenyl)(phenyl)phosphine oxide (CAS 803-20-3)
- Ethyl 2-(6-(naphthalen-2-ylthio)-9H-purin-9-yl)acetate (CAS 646509-78-6)
- 4-[[4-(2,7-Dimethylimidazo[1,2-α]pyridin-3-yl)-2-thiazolyl]amino]benzoic Acid (CAS 315704-15-5)
- 2-(5-Methylfuran-2-yl)benzonitrile (CAS 400751-12-4)
- 2-cyano-N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]acetamide (CAS 2321729-39-7)
- trans-Carboxy Glimepiride-d5 (CAS 1217718-14-3)
- 2-Bromo-3-fluorobenzaldehyde (CAS 891180-59-9)
- (5-Cyclopropoxy-2-methoxyphenyl)methanamine (CAS 1243355-99-8)
- N-(1-(2-Hydroxyethyl)-3-(thiophen-2-yl)-1H-pyrazol-5-yl)-1-(methylsulfonyl)piperidine-4-carboxamide (CAS 1219913-34-4)
- (R)-1-cyclopropylpiperidin-3-amine hydrochloride (CAS 1446424-25-4)
- 3-(2-chlorophenoxy)-2-butanone (CAS 3757-62-8)
- 2-Ethoxy-1-(3-(hydroxymethyl)piperidin-1-yl)ethan-1-one (CAS 1156724-72-9)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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