1,4-Dimethyl-9-{[3-(trifluoromethyl)phenyl]methyl}-9H-carbazole CAS 860648-99-3

Purity 97%+In StockPharmaceutical Standards
CAS No.860648-99-3
Molecular FormulaC22H18F3N
Molecular Weight353.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,4-Dimethyl-9-{[3-(trifluoromethyl)phenyl]methyl}-9H-carbazole CAS 860648-99-3 chemical structure

Description

The occurrence of 1,4-Dimethyl-9-{[3-(trifluoromethyl)phenyl]methyl}-9H-carbazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1,4-Dimethyl-9-{[3-(trifluoromethyl)phenyl]methyl}-9H-carbazole (CAS 860648-99-3) is a high-purity analytical reference standard with the molecular formula C22H18F3N and a molecular weight of 353.38 g/mol.

1,4-Dimethyl-9-{[3-(trifluoromethyl)phenyl]methyl}-9H-carbazole (C22H18F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H18F3N
Molecular Weight353.38 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms1

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