Methyl 3-(3-fluorophenyl)-3-(2-(4-(4-fluorophenyl)piperazin-1-yl)acetamido)propanoate CAS 860650-15-3
| CAS No. | 860650-15-3 |
| Molecular Formula | C22H25F2N3O3 |
| Molecular Weight | 417.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 3-(3-fluorophenyl)-3-(2-(4-(4-fluorophenyl)piperazin-1-yl)acetamido)propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 3-(3-fluorophenyl)-3-(2-(4-(4-fluorophenyl)piperazin-1-yl)acetamido)propanoate (CAS 860650-15-3), molecular formula C22H25F2N3O3 and molecular weight 417.45 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 3-(3-fluorophenyl)-3-(2-(4-(4-fluorophenyl)piperazin-1-yl)acetamido)propanoate (C22H25F2N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H25F2N3O3 |
| Molecular Weight | 417.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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