4-(3-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one CAS 860650-60-8
| CAS No. | 860650-60-8 |
| Molecular Formula | C9H8FN3O |
| Molecular Weight | 193.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(3-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(3-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860650-60-8) is a high-purity analytical reference standard with the molecular formula C9H8FN3O and a molecular weight of 193.18 g/mol.
The molecular framework of 4-(3-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (C9H8FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8FN3O |
| Molecular Weight | 193.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 5-[(3-fluorophenyl)methyl]-1,3,4-oxadiazol-2-amine (CAS 1016497-55-4)
- 5-[(2-fluorophenyl)methyl]-1,3,4-oxadiazol-2-amine (CAS 1016684-14-2)
- (5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl)methanamine (CAS 1082584-72-2)
- (1-(3-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1096130-65-2)
- (1-(4-Fluorophenyl)-1h-tetrazol-5-yl)methanamine (CAS 1105192-86-6)
- (1-(4-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1225046-93-4)
- (1-(2-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1247781-30-1)
- 5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3-amine (CAS 1260777-27-2)
Recommended Standards
- 4-(2-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-49-8)
- 4-(4-Fluorophenyl)-5-methyl-4H-1,2,4-triazol-3-ol (CAS 860650-96-0)
- 3-Azido-1-(4-fluorophenyl)propan-1-one (CAS 640734-61-8)
- 5-(4-Fluorobenzyl)-1,3,4-oxadiazol-2-amine (CAS 828911-26-8)
- 2-(4-Amino-5-bromo-3-(difluoromethyl)pyridin-2-yl)acetic acid (CAS 1805093-07-5)
- 5-((4-Chlorophenyl)sulfinyl)-N-ethyl-1,2,3-thiadiazole-4-carboxamide (CAS 306977-05-9)
- 2-Hydroxy-5-methoxyphenylboronic acid (CAS 259209-16-0)
- 4-Bromo-2-methylbenzylamine (CAS 376646-62-7)
- Cephalexin EP Impurity C (CAS 72528-40-6)
- 2-Cyano-3-chloropyridine (CAS 38180-46-0)
- 4-(Hydroxymethyl)benzo[d]oxazole-2-sulfonyl chloride (CAS 1807043-75-9)
- 3-Amino-3-(4-(trifluoromethyl)phenyl)acrylonitrile (CAS 71682-89-8)
- methyl 4-cyanobicyclo[2.1.1]hexane-1-carboxylate (CAS 2108908-57-0)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com