6-Iodoimidazo[1,2-a]pyridine-2-carbohydrazide CAS 860784-46-9
| CAS No. | 860784-46-9 |
| Molecular Formula | C8H7IN4O |
| Molecular Weight | 302.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Iodoimidazo[1,2-a]pyridine-2-carbohydrazide (CAS 860784-46-9), molecular formula C8H7IN4O and molecular weight 302.07 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution, 6-Iodoimidazo[1,2-a]pyridine-2-carbohydrazide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7IN4O |
| Molecular Weight | 302.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 4 |
Related Iodoimidazo Standards
- 3-Iodoimidazo[1,2-a]pyridine-7-carboxylic acid methyl ester (CAS 1009378-93-1)
- Methyl 6-iodoimidazo[1,2-a]pyridine-3-carboxylate (CAS 1359656-91-9)
- Methyl 3-iodoimidazo[1,2-a]pyridine-6-carboxylate (CAS 460087-82-5)
- Methyl 6-iodoimidazo[1,2-a]pyridine-2-carboxylate (CAS 2203317-58-0)
- Methyl 3-iodoimidazo[1,2-a]pyrimidine-2-carboxylate (CAS 1823921-37-4)
- N-(6-Iodoimidazo[1,2-a]pyridin-2-yl)acetamide (CAS 690258-22-1)
- Methyl 5-iodoimidazo[2,1-b]thiazole-2-carboxylate (CAS 1545412-45-0)
- (6-Iodoimidazo[1,2-b]pyridazin-2-yl)methanol (CAS 1005788-25-9)
Recommended Standards
- 6-Iodo-8-methylquinazoline-2,4(1H,3H)-dione (CAS 830343-35-6)
- 8-Iodo-6-methylquinazoline-2,4(1H,3H)-dione (CAS 667916-39-4)
- 6-Iodo-4-methyl-1H-indazole-3-carboxylic acid (CAS 885521-24-4)
- Methyl 3-iodo-1H-indazole-4-carboxylate (CAS 885521-54-0)
- 2-(4-Chlorophenoxy)-1-(piperazin-1-yl)ethan-1-one (CAS 143999-83-1)
- 4-chloro-3-methoxy-N-methylaniline (CAS 1224684-89-2)
- 2-(4-Chlorophenyl)thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine (CAS 866019-98-9)
- Carteolol Impurity 35 (CAS CATO-C4X-228735)
- (R)-8-Fluoro-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1798335-53-1)
- Methyl 4-(n-(piperidin-4-yl)sulfamoyl)benzoate hydrochloride (CAS 1286264-69-4)
- Potassium 2-(4-(N-Boc)-piperazin-1-yl)ethoxymethyltrifluoroborate (CAS 1452383-14-0)
- 1-(1-Ethyl-1h-pyrazol-5-yl)-2-(isopropylamino)ethan-1-ol (CAS 1494529-47-3)
- Silver Diethyldithiocarbamate (CAS 1470-61-7)
- Peptide Impurity 05 (CAS 2322924-83-2)
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