1-(Cyclopropylmethyl)-4-(4-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 860784-97-0
| CAS No. | 860784-97-0 |
| Molecular Formula | C13H14FN3O |
| Molecular Weight | 247.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Cyclopropylmethyl)-4-(4-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one.
1-(Cyclopropylmethyl)-4-(4-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860784-97-0), molecular formula C13H14FN3O and molecular weight 247.27 g/mol, is a CATO reference standard with documented purity and traceability.
1-(Cyclopropylmethyl)-4-(4-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (C13H14FN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Cyclopropylmethyl)-4-(4-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14FN3O |
| Molecular Weight | 247.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopropylmethyl Standards
- 1-(Cyclopropylmethyl)-4-(2-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860789-05-5)
- 4-(Cyclopropylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-7-carboxylic acid (CAS 1707594-78-2)
- Ethyl 3-(cyclopropylmethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-carboxylate (CAS 1923082-74-9)
- n-(Cyclopropylmethyl)-2-(3-(trifluoromethyl)-1h-pyrazol-1-yl)acetamide (CAS 1281083-58-6)
- N-(Cyclopropylmethyl)-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine (CAS 943058-09-1)
- 1-(Cyclopropylmethyl)-4-iodo-1H-imidazole (CAS 1334675-62-5)
- 1-(Cyclopropylmethyl)-4-iodopyrazole (CAS 1340571-52-9)
- 1-(Cyclopropylmethyl)-5-iodo-1H-pyrazole (CAS 1345471-39-7)
Recommended Standards
- 1-[5-(2-nitrophenyl)thiophen-2-yl]ethan-1-one (CAS 70013-40-0)
- 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid hydrazide (CAS 380474-18-0)
- 1-Ethyl-N-[(4-fluorophenyl)methyl]-1h-pyrazole-4-carboxamide (CAS 515831-20-6)
- 1-(2-Cyano-3-fluorophenyl)piperidine-4-carboxamide (CAS 262433-40-9)
- CL 218872 (CAS 66548-69-4)
- 2-(Difluoromethyl)-3-hydroxy-5-methylpyridine-6-acetonitrile (CAS 1805451-59-5)
- Ethyl 4,4-difluoro-2-methoxy-3-oxobutanoate (CAS 840521-79-1)
- 5-(tert-Butyl)-4-((4-hydroxy-6-(4-hydroxyphenethyl)-6-isopropyl-2-oxo-5,6-dihydro-2H-pyran-3-yl)thio)-2-methylphenyl 4-cyanobenzenesulfonate (CAS 263842-84-8)
- Reactive Orange 14 (CAS 12225-86-4)
- 1,2-Benzenedicarboxylic acid, dinonyl ester, branched and linear (CAS 68515-45-7)
- Glauberite (CAS 13767-89-0)
- (3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)(tert-butyl)dimethylsilane (CAS 1218789-51-5)
- 4-(Bicyclo[2.2.1]heptan-2-yl)butan-2-amine (CAS 1558896-39-1)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com