4-(3-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one CAS 860786-46-5
| CAS No. | 860786-46-5 |
| Molecular Formula | C18H16F3N3O2 |
| Molecular Weight | 363.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 363.33 g/mol gives 4-(3-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(3-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-46-5), a certified reference material (molecular formula C18H16F3N3O2, MW 363.33 g/mol) for analytical method development and quality control.
4-(3-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (C18H16F3N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16F3N3O2 |
| Molecular Weight | 363.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methoxyphenyl Standards
- 1-[(4-Methoxyphenyl)methyl]-3-methyl-4-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 861206-76-0)
- 4-(4-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-14-6)
- 4-[(4-Methoxyphenyl)sulfanyl]-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 338418-07-8)
- 1030102-15-8 1-[4-(2-Methoxyphenyl)piperazin-1-yl]isoquinoline-4-carboxylic acid MFCD14281719 (CAS 1030102-15-8)
- 1-[(5Z)-5-{[(4-methoxyphenyl)amino]methylidene}-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyrrolidine-2,5-dione (CAS 400076-20-2)
- 4-(4-Methoxyphenyl)-2,6-diphenylpyrimidine-5-carbonitrile (CAS 89058-96-8)
- N-(2-Methoxyphenyl)-2-((3-methyl-4-oxo-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-7-yl)thio)acetamide (CAS 869073-92-7)
- 6-(4-Methoxyphenyl)benzo[b]pyrrolo[1,2-d][1,4]thiazepin-7-yl acetate (CAS 131403-76-4)
Recommended Standards
- 2-N-Acetyl-1’,2’-di-O-acetyl-6-biopterin (CAS 81827-31-8)
- 5-Methyl-2-(2-phenoxyethyl)-4-(3-(trifluoromethyl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-75-9)
- N-(4-(2-Methoxyphenoxy)but-2-yn-1-yl)-2-(trifluoromethyl)benzamide (CAS 1421442-70-7)
- 6,7-Dimethoxy-N-(2-(trifluoromethyl)benzyl)quinazolin-4-amine (CAS 477855-26-8)
- 113246-41-6 5-Acetyl-4-methylpyrimidin-2(1H)-one 5-acetyl-4-methyl-2(1H)-pyrimidinone (CAS 113246-41-6)
- 7-bromo-8-hydroxyquinoline (CAS 13019-32-4)
- 5-(((6-Chloropyridin-3-yl)methyl)thio)-4h-1,2,4-triazol-3-amine (CAS 1094626-28-4)
- 2-(Tert-butyl) 3-ethyl (1R,3S,5S)-5-(hydroxymethyl)-2-azabicyclo[3.1.0]Hexane-2,3-dicarboxylate (CAS 1386461-22-8)
- 1-(4-Methyl-1,3-thiazol-2-yl)piperidine-3-carboxylic acid (CAS 927803-57-4)
- 1-Cyclohexylcyclopropan-1-amine (CAS 388095-20-3)
- N1-(4-Methoxycyclohexyl)ethane-1,2-diamine (CAS 1353959-23-5)
- 1-(2-((2-Chlorophenyl)amino)thiazol-5-yl)-2,2-dimethylpropan-1-one (CAS 339022-41-2)
- 3-(3-(3-Methoxyphenyl)-2,4-dioxoimidazolidin-1-yl)benzoic acid (CAS 651748-52-6)
- Lixisenatide (CAS 320367-13-3（free base）)
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