N-(3-Chlorophenyl)-6-phenyl-2-(pyridin-3-yl)pyrimidine-4-carboxamide CAS 860787-58-2
| CAS No. | 860787-58-2 |
| Molecular Formula | C22H15ClN4O |
| Molecular Weight | 386.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(3-Chlorophenyl)-6-phenyl-2-(pyridin-3-yl)pyrimidine-4-carboxamide (C22H15ClN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-(3-Chlorophenyl)-6-phenyl-2-(pyridin-3-yl)pyrimidine-4-carboxamide (CAS 860787-58-2), molecular formula C22H15ClN4O and molecular weight 386.83 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3-Chlorophenyl)-6-phenyl-2-(pyridin-3-yl)pyrimidine-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H15ClN4O |
| Molecular Weight | 386.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 2-[(2-Chlorophenyl)methyl]-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepine-1,3-dione (CAS 1775360-47-8)
- 2-[(3-Chlorophenyl)methyl]-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepine-1,3-dione (CAS 1775403-23-0)
- 2-[(3-Chlorophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (CAS 1775444-86-4)
- 2-[(2-Chlorophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (CAS 1775524-25-8)
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- 4-(2-Chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)piperazine-1-carboxamide (CAS 685107-77-1)
- 4-[5-(2-chlorophenyl)-3-(2-methoxyphenyl)-4,5-dihydro-1h-pyrazol-1-yl]-4-oxobutanoic acid (CAS 378211-39-3)
- 6-((3-Chlorophenyl)amino)-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione (CAS 58221-90-2)
Recommended Standards
- Ethyl 4-(1-(4-chlorophenyl)-5-oxopyrrolidine-3-carboxamido)benzoate (CAS 328090-80-8)
- Tolvaptan Impurity 123 (CAS CATO-C4X-1955123)
- Ethyl 3-({[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]carbonyl}amino)benzoate (CAS 897739-23-0)
- (Z)-N-(1-Chloro-1-(2-fluorophenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl)benzamide (CAS 1323140-60-8)
- (1-((3-Fluorophenyl)sulfonyl)pyrrolidin-3-yl)methanamine (CAS 1832067-64-7)
- (2R,3S,4S,5R,6R)-6-(acetoxymethyl)-4-(carbamoyloxy)tetrahydro-2H-pyran-2,3,5-triyl triacetate (CAS 99748-11-5)
- 3,4,5-Trimethylbenzoic Acid (CAS 1076-88-6)
- 2-(4-Bromopyridin-2-yl)isothiazolidine 1,1-dioxide (CAS 1597022-64-4)
- 2-(1-phenylethyl)oxirane (CAS 15701-82-3)
- N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide (CAS 182007-86-9)
- 3-(3-Acetylphenyl)phenol (CAS 365427-02-7)
- (R)-2-(3-(Benzyl(ethyl)amino)pyrrolidin-1-yl)acetic acid (CAS 1354009-89-4)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoic acid (CAS 212394-94-0)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
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