4-[(tert-butyldimethylsilyl)oxy]but-2-yn-1-ol CAS 86120-46-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(tert-butyldimethylsilyl)oxy]but-2-yn-1-ol.

CATO supplies 4-[(tert-butyldimethylsilyl)oxy]but-2-yn-1-ol (CAS 86120-46-9), a certified reference material (molecular formula C10H20O2Si, MW 200.35 g/mol) for analytical method development and quality control.

Structurally, 4-[(tert-butyldimethylsilyl)oxy]but-2-yn-1-ol (C10H20O2Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 200.35 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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