(E)-2-(1-(5-methyl-4-phenylthiazol-2-yl)-2-(2-(trifluoromethyl)phenyl)vinyl)thiazol-4-ol CAS 861206-98-6

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(E)-2-(1-(5-methyl-4-phenylthiazol-2-yl)-2-(2-(trifluoromethyl)phenyl)vinyl)thiazol-4-ol (CAS 861206-98-6), molecular formula C22H15F3N2OS2 and molecular weight 444.49 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (E)-2-(1-(5-methyl-4-phenylthiazol-2-yl)-2-(2-(trifluoromethyl)phenyl)vinyl)thiazol-4-ol (C22H15F3N2OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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