(3E)-3-({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methylidene)-2,3-dihydro-1H-indol-2-one CAS 861207-72-9
| CAS No. | 861207-72-9 |
| Molecular Formula | C22H17ClN2O3 |
| Molecular Weight | 392.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3E)-3-({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methylidene)-2,3-dihydro-1H-indol-2-one (CAS 861207-72-9) is a high-purity analytical reference standard with the molecular formula C22H17ClN2O3 and a molecular weight of 392.83 g/mol.
Structurally, (3E)-3-({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methylidene)-2,3-dihydro-1H-indol-2-one (C22H17ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 392.83 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3E)-3-({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methylidene)-2,3-dihydro-1H-indol-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H17ClN2O3 |
| Molecular Weight | 392.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- 6-(4-(6-Chloropyridin-2-yl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione (CAS 339012-75-8)
- 2-(2-Chloropyridin-3-yl)-1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazole (CAS 338411-20-4)
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