N-(4-(4-(hydroxymethyl)piperidin-1-yl)benzyl)-4-methylbenzenesulfonamide CAS 861210-21-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-(4-(hydroxymethyl)piperidin-1-yl)benzyl)-4-methylbenzenesulfonamide.

N-(4-(4-(hydroxymethyl)piperidin-1-yl)benzyl)-4-methylbenzenesulfonamide (CAS 861210-21-1), molecular formula C20H26N2O3S and molecular weight 374.50 g/mol, is a CATO reference standard with documented purity and traceability.

N-(4-(4-(hydroxymethyl)piperidin-1-yl)benzyl)-4-methylbenzenesulfonamide (C20H26N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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