(2Z)-3-[(4-Fluoro-2-methylphenyl)amino]-1-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]but-2-en-1-one CAS 861212-89-7
| CAS No. | 861212-89-7 |
| Molecular Formula | C24H18F2N2O2 |
| Molecular Weight | 404.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2Z)-3-[(4-Fluoro-2-methylphenyl)amino]-1-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]but-2-en-1-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2Z)-3-[(4-Fluoro-2-methylphenyl)amino]-1-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]but-2-en-1-one (CAS 861212-89-7), molecular formula C24H18F2N2O2 and molecular weight 404.41 g/mol, is a CATO reference standard with documented purity and traceability.
(2Z)-3-[(4-Fluoro-2-methylphenyl)amino]-1-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]but-2-en-1-one (C24H18F2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2Z)-3-[(4-Fluoro-2-methylphenyl)amino]-1-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]but-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18F2N2O2 |
| Molecular Weight | 404.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
- (3-(1-((2-Fluoro-[1,1'-biphenyl]-4-yl)oxy)ethyl)-1H-pyrazol-1-yl)(4-fluorophenyl)methanone (CAS 477709-66-3)
- 4'-fluoro-5-hydroxy-4-(1,2,3,4-tetrahydroisoquinolin-1-yl)-6-(1H-1,2,4-triazol-1-yl)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 1005106-96-6)
- 4-(4-Fluoro-phenyl)-1-trityl-1H-pyrazole (CAS 936359-90-9)
- 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(2,2,3,3,4,4,5,5-octadeuteriopyrrolidin-1-yl)ethyl]-1H-pyrrole-3-carboxamide (CAS 1795134-78-9)
- ethyl 6-fluoro-1-methyl-2-oxo-4-(trifluoromethylsulfonyloxy)quinoline-3-carboxylate (CAS 2660228-78-2)
- 3-Fluoro-N-((2-(m-tolyl)benzo[d]oxazol-5-yl)carbamothioyl)benzamide (CAS 590394-08-4)
- 3-Fluoro-5-((7'-(methylsulfonyl)-3'-oxo-2',3'-dihydrospiro[[1,3]dioxolane-2,1'-inden]-4'-yl)oxy)benzonitrile (CAS 1672668-41-5)
- Benzyl (3-fluoro-4-(4-phenylpiperazin-1-yl)phenyl)carbamate (CAS 556801-41-3)
Recommended Standards
- 4-((2R,3R)-3-(Hydroxymethyl)-7-((E)-3-hydroxyprop-1-en-1-yl)-5-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-2,6-dimethoxyphenol (CAS 171674-89-8)
- Dimethyl 4,4'-(propane-1,3-diylbis(oxy))bis(3-methoxybenzoate) (CAS 130107-96-9)
- (E)-[1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethylidene]amino 3-(trifluoromethyl)benzoate (CAS 477858-05-2)
- N-(5-acetyl-4-methylthiazol-2-yl)-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 1209571-20-9)
- hydroxyethoxysilatrane (CAS 56929-77-2)
- 4-Bromo-2-cyano-6-iodobenzoic acid (CAS 1805183-51-0)
- 3-(5-methoxy-4-oxo-4H-pyran-2-yl)prop-2-enoic acid (CAS 72612-21-6)
- 1-Bromo-2,5-dichloro-4-isopropoxybenzene (CAS 1779132-17-0)
- 1-Bromo-4-chloro-2,5-difluorobenzene (CAS 172921-33-4)
- 5-(4-([4,2':6',4''-terpyridin]-4'-yl)phenoxy)isophthalic acid (CAS 1651867-07-0)
- 4-[1-(Boc-amino)cyclopropyl]phenylboronic Acid (CAS 1217500-58-7)
- 4-(3,5-Dimethylphenyl)-2-hydrazinylthiazole (CAS 886495-59-6)
- 2-amino-2-(1-naphthyl)ethanol (CAS 86217-42-7)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com