8-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid CAS 861236-55-7
| CAS No. | 861236-55-7 |
| Molecular Formula | C16H10ClNO3 |
| Molecular Weight | 299.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 299.71 g/mol gives 8-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid (CAS 861236-55-7), molecular formula C16H10ClNO3 and molecular weight 299.71 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid (C16H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 299.71 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10ClNO3 |
| Molecular Weight | 299.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-(4-Chloro-2,5-dimethoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1019371-72-2)
- 6-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid (CAS 116734-19-1)
- 2-Chloro-N-(9,10-dihydro-9,10-dioxo-2-anthracenyl)acetamide (CAS 143210-98-4)
- 1-(2-Chloro-4-nitrophenyl)-3-(1,3-dioxan-2-yl)propan-1-one (CAS 937040-35-2)
- 1-(5-Chloro-2,4-dimethoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 793727-58-9)
- 1-Chloro-4-(2-nitrophenoxy)naphthalene (CAS 400075-69-6)
- 2-Chloro-3-((4-hydroxyphenyl)amino)naphthalene-1,4-dione (CAS 64897-00-3)
- 2-Chloro-3-(2-oxoindolin-3-yl)benzohydrazide (CAS 82973-13-5)
Recommended Standards
- 8-Chloro-2-(3-hydroxyphenyl)quinoline-4-carboxylic acid (CAS 669739-31-5)
- 8-Chloro-4-hydroxy-N-(pyridin-2-yl)quinoline-3-carboxamide (CAS 951964-86-6)
- 8-Chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid (CAS 667412-65-9)
- Ethyl 4-chloro-7-cyano-5H-pyrido[3,2-b]indole-3-carboxylate (CAS 2681278-28-2)
- 6-Chloro-N4-isobutylpyrimidine-4,5-diamine (CAS 195252-59-6)
- 4-Phenyl-2-(pyridin-4-yl)oxazole-5-carboxylic acid (CAS 1245649-34-6)
- (3R,4S)-rel-4-(6-Methoxypyridin-3-yl)pyrrolidine-3-carboxylic acid dihydrochloride (CAS 1392212-96-2)
- 2-(Methylthio)-4-thien-2-ylpyrimidine (CAS 683274-58-0)
- 1-Methyl-3-(2-((quinolin-2-ylmethyl)thio)ethyl)guanidine (CAS 92885-55-7)
- N-(4-Bromophenyl)-1,1,1-trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide (CAS 191043-82-0)
- (S)-Methyl 1-((S)-1-(4-bromophenyl)ethyl)pyrrolidine-2-carboxylate (CAS 1313365-73-9)
- Des-D-Trp-Pasireotide (CAS CATO-C4X-20082)
- N3-benzylpyridine-2,3-diamine (CAS 79707-12-3)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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