6-(2,4-Difluorophenoxy)nicotinic acid CAS 862088-72-0
| CAS No. | 862088-72-0 |
| Molecular Formula | C12H7F2NO3 |
| Molecular Weight | 251.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-(2,4-Difluorophenoxy)nicotinic acid (CAS 862088-72-0), molecular formula C12H7F2NO3 and molecular weight 251.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-(2,4-Difluorophenoxy)nicotinic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 6-(2,4-Difluorophenoxy)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7F2NO3 |
| Molecular Weight | 251.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenoxy Standards
- 2-(2,4-difluorophenoxy)pyridine-4-carboxylic acid (CAS 1019364-36-3)
- 2-(2,5-Difluorophenoxy)isonicotinic acid (CAS 1199215-67-2)
- 1-(4-(3,4-Difluorophenoxy)phenyl)ethan-1-ol (CAS 1153088-54-0)
- 1-(4-(2,5-Difluorophenoxy)phenyl)ethan-1-ol (CAS 1478075-02-3)
- 175135-62-3 2-(2,4-difluorophenoxy)-3-nitropyridine 2-[2,4-bis(fluoranyl)phenoxy]-3-nitro-pyridine A811737 (CAS 175135-62-3)
- 2-(2,4-Difluorophenoxy)-5-nitropyridine (CAS 219865-86-8)
- 4-(3,4-Difluorophenoxy)benzoic acid (CAS 1153088-42-6)
- 4-(2,4-Difluorophenoxy)benzoic acid (CAS 748183-47-3)
Recommended Standards
- 4-bromo-3-methyl-thieno[2,3-c]pyridin-7-amine (CAS 2306278-38-4)
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- 3-(6-Nitro-4H-1,3-benzodioxin-8-yl)-2-propenoic acid (CAS 869472-63-9)
- 7-bromo-3-methylthieno[3,2-c]pyridin-4-amine (CAS 2306263-16-9)
- Rivaroxaban Impurity 32 (CAS 956904-18-0)
- 3-(2-Methyl-1H-imidazol-1-yl)propanenitrile (CAS 23996-55-6)
- Ethyl trans-Cinnamate-d5 (phenyl-d5) (CAS 856765-68-9)
- (2R,3R)-2,3-Dihydroxy-3-((4S,5R)-2-hydroxy-5-(hydroxymethyl)-1,3,2-dioxaborolan-4-yl)propanoic acid (CAS 87-46-7)
- N'-(2-chloroacetyl)-8-methyl-8H-thieno[2,3-b]indole-2-carbohydrazide (CAS 477855-76-8)
- 4-(4-Methoxybenzyloxy)-2-fluorobenzonitrile (CAS 1242152-56-2)
- 4,4,4-Trifluoro-1-(2-fluorophenyl)butane-1,3-dione (CAS 111102-82-0)
- (S)-tert-Butyl ((1-(2-aminoethyl)pyrrolidin-2-yl)methyl)(isopropyl)carbamate (CAS 1354002-77-9)
- 2-Acetamido-3-(tetrahydro-2h-pyran-4-yl)propanoic acid (CAS 1339135-35-1)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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