Maropitant Impurity 8(M9) CAS 862543-55-3
| CAS No. | 862543-55-3 |
| Molecular Formula | C27H30N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Maropitant Impurity 8(M9).
Maropitant Impurity 8(M9) (CAS 862543-55-3) is a certified pharmaceutical impurity reference standard with the molecular formula C27H30N2C10H16O4S and a molecular weight of 614.85 g/mol.
The molecular framework of Maropitant Impurity 8(M9) (C27H30N2C10H16O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Maropitant Impurity 8(M9) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H30N2 C10H16O4S |
| Molecular Weight | 614.85 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Maropitant Standards
- Maropitant Impurty 3(M10) (CAS 142035-23-2)
- Maropitant Impurty 3(M10) TFA (CAS 142035-23-2（free base）)
- Maropitant (CAS 147116-67-4)
- Maropitant Impurity 13 (CAS 155681-48-4)
- Maropitant Impurity 7 (CAS 2243127-08-2)
- Maropitant Impurity 17 (CAS 2243127-12-8)
- Maropitant Citrate Hydrate (CAS 359875-09-5)
- Maropitant Impurty 6(M4) (CAS 52455-71-7)
Recommended Standards
- Relugolix Impurity 202 (CAS CATO-C4X-2429202)
- Tadalafil impurity 125 (CAS CATO-C4X-1087125)
- Atorvastatin Impurity 108 Pivalate (CAS 676260-66-5 (free base))
- 1H-Pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 223376-47-4)
- 1-(4-Nitrophenyl)-1h-1,2,3-triazole-4-carbaldehyde (CAS 113934-26-2)
- 7-Hydroxy-3-(1-phenyl-1h-pyrazol-4-yl)-2-(trifluoromethyl)-4h-chromen-4-one (CAS 51412-01-2)
- 5'-Bromo-2',3'-dihydrospiro[cyclobutane-1,1'-inden]-2'-amine (CAS 1367024-03-0)
- (E)-1-methyl-4-(3-oxobut-1-en-1-yl)pyridin-1-ium (CAS 471289-96-0)
- Methyl 1-methyl-1H-indazole-3-carboxylate (CAS 109216-60-6)
- Glucagon-like peptide 2 (CAS 89750-15-2)
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