4-Amino-2-chloro-5-hydroxy-N-methylbenzenesulfonamide CAS 86264-31-5

Description

Compared with other compounds in its class, the molecular weight of 236.68 g/mol gives 4-Amino-2-chloro-5-hydroxy-N-methylbenzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Amino-2-chloro-5-hydroxy-N-methylbenzenesulfonamide (CAS 86264-31-5), molecular formula C7H9ClN2O3S and molecular weight 236.68 g/mol, is a CATO reference standard with documented purity and traceability.

4-Amino-2-chloro-5-hydroxy-N-methylbenzenesulfonamide (C7H9ClN2O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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