2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(2-chlorophenyl)acetamide CAS 863182-69-8
| CAS No. | 863182-69-8 |
| Molecular Formula | C16H13Cl2NO4 |
| Molecular Weight | 354.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(2-chlorophenyl)acetamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(2-chlorophenyl)acetamide (CAS 863182-69-8), molecular formula C16H13Cl2NO4 and molecular weight 354.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(2-chlorophenyl)acetamide (C16H13Cl2NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(2-chlorophenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl2NO4 |
| Molecular Weight | 354.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(4-chlorophenyl)acetamide (CAS 792945-82-5)
- 2-Chloro-1-(5-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)thiophen-2-yl)ethan-1-one (CAS 338411-65-7)
- 4-(4-Chloro-2-(2-chlorobenzoyl)phenyl)pyrimidine-5-carbonitrile (CAS 87999-64-2)
- 3-Chloro-N-(3-chloroquinoxalin-2-yl)benzenesulfonamide (CAS 743444-94-2)
- 4-Chloro-N-(3-chloroquinoxalin-2-yl)benzenesulfonamide (CAS 522628-95-1)
- (3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 1083326-71-9)
- 1797008-31-1 2-Chloro-N-[4-[(4-methoxyphenyl)methoxy]-2-chloro-6-methylphenyl]acetamide (CAS 1797008-31-1)
- 1-Benzyl-5-chloro-2-(6-chloropyridin-3-yl)-1H-1,3-benzodiazole (CAS 400075-97-0)
Recommended Standards
- 2-Iodotriphenylene (CAS 1228778-59-3)
- N-(5-(5-Bromofuran-2-yl)-1,3,4-oxadiazol-2-yl)-2-(thiophen-2-yl)acetamide (CAS 1171196-79-4)
- 3-Iodo-4-methoxy-2-phenyl-4,5,6,7-tetrahydrobenzofuran (CAS 866558-05-6)
- 2-(4-(2-(2,4-Dichlorophenoxy)acetamido)phenyl)acetic acid (CAS 1012207-68-9)
- (S)-2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-amine hydrochloride (CAS 929642-58-0)
- 2,5-Dioxopyrrolidin-1-yl N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-L-lysinate (CAS 132307-50-7)
- 5-Bromo-1H-pyrrolo[3,2-b]pyridine-2-carbaldehyde (CAS 1367950-88-6)
- n-(5-Bromo-2-methoxybenzyl)tetrahydro-2h-pyran-3-amine (CAS 1406095-35-9)
- 1,4-Dibromo-2-(difluoromethyl)benzene (CAS 1214383-36-4)
- 1-(Quinolin-5-yl)guanidine (CAS 781557-39-9)
- (E)-3-(5-fluoro-2-(trifluoromethoxy)phenyl)acrylic acid (CAS 1092460-94-0)
- 3-Bromo-7-ethyl-1H-indole (CAS 1037153-00-6)
- 1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]propan-1-amine (CAS 1248076-55-2)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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