1-[4-(difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid CAS 863209-30-7
| CAS No. | 863209-30-7 |
| Molecular Formula | C18H19F2N3O3 |
| Molecular Weight | 363.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[4-(difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid.
1-[4-(difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid (CAS 863209-30-7) is a high-purity analytical reference standard with the molecular formula C18H19F2N3O3 and a molecular weight of 363.36 g/mol.
Based on its molecular formula C18H19F2N3O3, 1-[4-(difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 363.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[4-(difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H19F2N3O3 |
| Molecular Weight | 363.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related difluoromethyl Standards
- Ethyl 2-(4-(difluoromethyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1052634-25-9)
- 2-(Difluoromethyl)-5-iodo-4-methoxypyridine-3-sulfonamide (CAS 1804864-67-2)
- 2-(Difluoromethyl)-4-iodo-3-methoxypyridine-6-sulfonamide (CAS 1805091-17-1)
- 4-(Difluoromethyl)-2-iodo-6-methoxypyridine-3-sulfonamide (CAS 1805420-49-8)
- 4-(Difluoromethyl)-2-iodo-5-methoxypyridine-3-sulfonamide (CAS 1805533-89-4)
- 4-(Difluoromethyl)-5-iodo-2-methoxypyridine-3-sulfonamide (CAS 1805533-96-3)
- 4-(Difluoromethyl)-6-iodo-2-methoxypyridine-3-sulfonamide (CAS 1805546-37-5)
- 2-(Difluoromethyl)-6-iodo-5-methoxypyridine-3-sulfonamide (CAS 1805603-08-0)
Recommended Standards
- 1-[3-(4-Fluorophenyl)-2,1-benzisoxazol-5-yl]-1-ethanone N-(2-fluorophenyl)hydrazone (CAS 306978-26-7)
- 1-{4-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]phenyl}-1H-pyrrole-2,5-dione (CAS 949923-55-1)
- 1,2-Dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-13(12H)-one (CAS 28342-33-8)
- 2-((3,5-Bis(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1-carboxylic acid (CAS 497060-80-7)
- 3-Amino-1-(4-(pyrazin-2-yl)piperazin-1-yl)propan-1-one dihydrochloride (CAS 1311317-09-5)
- 4-Isopropyl-3-methylpyridine (CAS 76160-91-3)
- 2-(Ethoxymethyl)-4-propylpyrimidine-5-carboxylic acid (CAS 1485002-19-4)
- (2-Aminoethyl)(methyl)(methylimino)-lambda6-sulfanone oxalate (CAS 1955558-24-3)
- Ethyl 2,3,4-tri-O-benzyl-1-thio-β-D-glucopyranoside (CAS 126461-54-9)
- 4-(2-(2-Bromoethoxy)phenyl)-4H-1,2,4-triazole (CAS 1223748-41-1)
- Undec-2-en-1-ol (CAS 37617-03-1)
- 5-Iodo-2-isopropylpyrimidine (CAS 1447607-83-1)
- 1-(Furan-2-yl)cyclopropanol (CAS 120284-29-9)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com