6-Fluoro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid CAS 86323-66-2
| CAS No. | 86323-66-2 |
| Molecular Formula | C10H10FNO2 |
| Molecular Weight | 195.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Fluoro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 86323-66-2), molecular formula C10H10FNO2 and molecular weight 195.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-Fluoro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 195.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-Fluoro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10FNO2 |
| Molecular Weight | 195.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3-(3-Fluoro-4-methoxyphenyl)acrylamide (CAS 1000568-53-5)
- 7-Fluoro-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 103362-10-3)
- 2-Fluoro-4-acetamidoacetophenone (CAS 112279-55-7)
- 3-fluoro-4-(2-methoxyethoxy)benzonitrile (CAS 1153104-44-9)
- (R)-6-fluoro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1161833-80-2)
- 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE-2-CARBOXYLIC ACID (CAS 1218657-56-7)
- 6-Fluoro-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1242014-94-3)
- 7-fluoro-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1260641-74-4)
Recommended Standards
- 6-(4-Fluorophenyl)-3-morpholinone (CAS 951626-54-3)
- 6-Fluoro-7-hydroxy-4-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 2378746-11-1)
- 5-sulfamoylfuran-2-carboxylic acid (CAS 98027-63-5)
- 8-Fluoro-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one (CAS 304854-40-8)
- 1H-Pyrrolo[1,2-b]indazole (CAS 344793-57-3)
- 3-Amino-3-cyclopropylpropanoic Acid (CAS 331633-72-8)
- 4-(4-(3-Fluorophenyl)-4H-1,2,4-triazol-3-yl)piperidine (CAS 1369042-61-4)
- N-[5-(Trifluoromethyl)pyridin-2-yl]valine (CAS 1028251-32-2)
- 2-(5-Fluoro-2-methoxyphenyl)-2-oxoacetic acid (CAS 1094355-95-9)
- (6-Amino-[3,3'-bipyridin]-4-yl)methanol (CAS 1227499-87-7)
- 4-Chlorobutyraldehyde Diethyl Acetal (CAS 6139-83-9)
- prop-2-en-1-yl(3,3,3-trifluoropropyl)amine (CAS 1342622-65-4)
- 3,4-Dihydro-6-methoxy-7-(phenylmethoxy)-1-[[4-(phenylmethoxy)phenyl]methyl]-isoquinoline (CAS 500577-65-1)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com