Obeticholic Acid Impurity 19 CAS 863239-60-5
| CAS No. | 863239-60-5 |
| Molecular Formula | C28H47NO5 |
| Molecular Weight | 477.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Obeticholic Acid Impurity 19 (CAS 863239-60-5, C28H47NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Obeticholic Acid Impurity 19 (C28H47NO5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H47NO5 |
| Molecular Weight | 477.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Obeticholic Standards
- Obeticholic Acid Impurity 43 (CAS CATO-C4X-115343)
- Obeticholic Acid Impurity 13 (CAS CATO-C4X-115323)
- Obeticholic Acid Impurity 41 (CAS CATO-C4X-115341)
- Obeticholic Acid Impurity 50 (CAS CATO-C4X-115350)
- Obeticholic Acid Impurity 46 (CAS 2241648-47-3)
- Obeticholic Acid Impurity 20 (CAS CATO-C4X-115320)
- Obeticholic Acid Impurity 42 (CAS CATO-C4X-115342)
- Obeticholic Acid Impurity 52 (CAS 60354-42-9)
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