Methyl 3-cyclohexyl-2-(2-hydroxyphenyl)-1H-indole-6-carboxylate CAS 863578-50-1
| CAS No. | 863578-50-1 |
| Molecular Formula | C22H23NO3 |
| Molecular Weight | 349.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 3-cyclohexyl-2-(2-hydroxyphenyl)-1H-indole-6-carboxylate (C22H23NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Methyl 3-cyclohexyl-2-(2-hydroxyphenyl)-1H-indole-6-carboxylate (CAS 863578-50-1), molecular formula C22H23NO3 and molecular weight 349.42 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-cyclohexyl-2-(2-hydroxyphenyl)-1H-indole-6-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23NO3 |
| Molecular Weight | 349.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
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Recommended Standards
- Methyl 2'-oxo-1'-phenyl-3,4-dihydro-1h-spiro[naphthalene-2,3'-piperidine]-6-carboxylate (CAS 2028324-97-0)
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- Methyl (s)-2'-oxo-1'-phenyl-3,4-dihydro-1h-spiro[naphthalene-2,3'-piperidine]-6-carboxylate (CAS 2028324-99-2)
- Prasugrel Impurity 36 (CAS 866761-69-5)
- 1-<I>N</I>-tert-butoxycarbonylpiperidine-4-boronic acid pinacol ester (CAS 1048970-17-7)
- 7-[2-(2-methylthiazol-4-yl)ethynyl]-1,2-benzoxazol-3-amine (CAS 2498757-48-3)
- (S)-2-Amino-N-isopropyl-3-methyl-N-(1-methyl-piperidin-4-yl)-butyramide (CAS 1401667-33-1)
- 3-(Chloromethyl)-1-(2-chlorophenyl)-1h-pyrazole (CAS 1466733-04-9)
- Triamcinolone Acetonide Impurity 45 (CAS CATO-C4X-132645)
- 3-(5-Chloro-2-methoxyphenyl)-4-nitro-1H-pyrazole (CAS 1708168-80-2)
- Rebamipide Impurity 39 (CAS CATO-C4X-152339)
- 3-(4-Hydroxy-1,3-dioxo-1,3-dihydroisoindol-2-yl)propionic acid tert-butyl ester (CAS 1256450-55-1)
- 1-(4-Chlorophenyl)-3-(3-(difluoromethoxy)phenyl)urea (CAS 886542-48-9)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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