1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)ethanone CAS 864754-06-3
| CAS No. | 864754-06-3 |
| Molecular Formula | C12H17BO3S |
| Molecular Weight | 252.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)ethanone.
1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)ethanone (CAS 864754-06-3), molecular formula C12H17BO3S and molecular weight 252.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)ethanone (C12H17BO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17BO3S |
| Molecular Weight | 252.14 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Sulfur Atoms | 1 |
Related Tetramethyl Standards
- 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-3-yl)ethan-1-one (CAS 1040281-85-3)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxamide (CAS 1257996-76-1)
- (S)-1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-2-ol (CAS 1282530-88-4)
- (R)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-1-ol (CAS 2505078-37-3)
- (S)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-1-ol (CAS 2505078-45-3)
- 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5-dihydro-1H-pyrrolo[3,4-b]pyrrol-6-one (CAS 2052290-76-1)
- 3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine (CAS 1160614-73-2)
- 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine (CAS 1873385-99-9)
Recommended Standards
- 1-(2,4-Difluorophenyl)-4,4,4-trifluorobutane-1,3-dione (CAS 64287-18-9)
- 1-(3,4-Difluorophenyl)-4,4,4-trifluorobutane-1,3-dione (CAS 74445-75-3)
- (3-Chlorophenyl)(4-chlorophenyl)methanamine (CAS 701212-44-4)
- 1-{2,4-dichloropyrrolo[2,1-f][1,2,4]triazin-7-yl}propan-2-one (CAS 2090837-31-1)
- tert-Butyl 3-((((trifluoromethyl)sulfonyl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 305329-96-8)
- 4-Hydroxy-7-phenoxyisobenzofuran-1,3-dione (CAS 89450-88-4)
- 6-bromo-3-chloro-9H-pyrido[2,3-b]indole (CAS 1175675-58-7)
- 1-Methyl-1H-imidazole-5-carbonyl chloride hydrochloride (CAS 343569-06-2)
- 4-Chloro-3-nitrophenylboronic Acid Pinacol Ester (CAS 913836-26-7)
- 4-(4-Methyl-4h-1,2,4-triazol-3-yl)butanoic acid (CAS 1248637-07-1)
- 1-phenylpyrrolidin-3-ol (CAS 90874-96-7)
- (R)-4-(((tert-Butyldiphenylsilyl)oxy)methyl)oxazolidin-2-one (CAS 1453082-82-0)
- 4-Chloro-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine (CAS 331761-46-7)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
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