2-Chloro-1-difluoromethoxy-4-isothiocyanato-benzene CAS 865149-80-0
| CAS No. | 865149-80-0 |
| Molecular Formula | C8H4ClF2NOS |
| Molecular Weight | 235.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-1-difluoromethoxy-4-isothiocyanato-benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Chloro-1-difluoromethoxy-4-isothiocyanato-benzene (CAS 865149-80-0), a certified reference material (molecular formula C8H4ClF2NOS, MW 235.64 g/mol) for analytical method development and quality control.
2-Chloro-1-difluoromethoxy-4-isothiocyanato-benzene (C8H4ClF2NOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4ClF2NOS |
| Molecular Weight | 235.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-(2-fluorobenzoyl)pyridine (CAS 1187167-94-7)
- 2-Chloro-7-(difluoromethoxy)benzo[d]thiazole (CAS 1261629-26-8)
- (3-Chloro-5-fluorophenyl)(pyridin-2-yl)methanone (CAS 1261754-42-0)
- 2-Chloro-6-(difluoromethoxy)benzo[d]thiazole (CAS 1261786-73-5)
- (4-Chloro-3-fluorophenyl)(pyridin-2-yl)methanone (CAS 1261868-06-7)
- 5-(4-Chloro-2-fluorophenyl)nicotinaldehyde (CAS 1346691-91-5)
- 5-(4-Chloro-3-fluorophenyl)nicotinaldehyde (CAS 1346691-96-0)
- 5-(3-Chloro-2-fluorophenyl)nicotinaldehyde (CAS 1346692-07-6)
Recommended Standards
- 1-Chloro-4-(methylsulfonyl)-2-nitrobenzene (CAS 97-07-4)
- 2-Chloro-4-methylsulfonyl-1-nitrobenzene (CAS 60854-81-1)
- 1-Chloro-4-((nitromethyl)sulfonyl)benzene (CAS 66073-97-0)
- 2-Chloro-5-sulfamoylbenzoic acid (CAS 97-04-1)
- (S)-2-((tert-butoxycarbonyl)amino)-2-(1-methyl-1H-pyrazol-4-yl)acetic acid (CAS 2165612-79-1)
- (2-Fluoro-4-iodophenyl)methanol (CAS 1039646-78-0)
- 2-Bromo-1-(2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)ethan-1-one (CAS 872539-32-7)
- 3-(3,5-Dichlorophenyl)morpholine (CAS 943654-53-3)
- trans-2-(3-Fluoro-4-methylphenyl)cyclopentanol (CAS 933674-43-2)
- Ethyl 2-(4-(aminomethyl)phenyl)thiazole-4-carboxylate (CAS 886368-46-3)
- Ethyl 1-(3-aminobenzyl)piperidine-4-carboxylate (CAS 306937-22-4)
- 2-Chloro-6-hydroxynicotinaldehyde (CAS 1227592-84-8)
- 3-(2-Hydroxyethyl)-2,7-dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 84946-18-9)
- Hexapeptide-10 (CAS 146439-94-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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