(E)-1-(4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl)-3-(p-tolylamino)prop-2-en-1-one CAS 865658-20-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-1-(4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl)-3-(p-tolylamino)prop-2-en-1-one.

CATO supplies (E)-1-(4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl)-3-(p-tolylamino)prop-2-en-1-one (CAS 865658-20-4), a certified reference material (molecular formula C22H22N2O, MW 330.42 g/mol) for analytical method development and quality control.

(E)-1-(4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl)-3-(p-tolylamino)prop-2-en-1-one (C22H22N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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