N-(4-methylbenzyl)-2-(pyridin-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide CAS 865660-38-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-methylbenzyl)-2-(pyridin-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide.

CATO supplies N-(4-methylbenzyl)-2-(pyridin-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 865660-38-4), a certified reference material (molecular formula C19H15F3N4O, MW 372.34 g/mol) for analytical method development and quality control.

The molecular framework of N-(4-methylbenzyl)-2-(pyridin-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide (C19H15F3N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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