2-((2-(Tert-butylthio)ethyl)amino)-3-chloronaphthalene-1,4-dione CAS 866008-89-1
| CAS No. | 866008-89-1 |
| Molecular Formula | C16H18ClNO2S |
| Molecular Weight | 323.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((2-(Tert-butylthio)ethyl)amino)-3-chloronaphthalene-1,4-dione (CAS 866008-89-1) is a high-purity analytical reference standard with the molecular formula C16H18ClNO2S and a molecular weight of 323.84 g/mol.
The molecular framework of 2-((2-(Tert-butylthio)ethyl)amino)-3-chloronaphthalene-1,4-dione (C16H18ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-((2-(Tert-butylthio)ethyl)amino)-3-chloronaphthalene-1,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H18ClNO2S |
| Molecular Weight | 323.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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