2-Chloro-N-(2-(phenethylamino)pyridin-3-yl)nicotinamide CAS 866010-52-8
| CAS No. | 866010-52-8 |
| Molecular Formula | C19H17ClN4O |
| Molecular Weight | 352.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-N-(2-(phenethylamino)pyridin-3-yl)nicotinamide (C19H17ClN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Chloro-N-(2-(phenethylamino)pyridin-3-yl)nicotinamide (CAS 866010-52-8), molecular formula C19H17ClN4O and molecular weight 352.82 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H17ClN4O |
| Molecular Weight | 352.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- Methyl 4-({3-methyl-2-oxo-4-[3-(trifluoromethyl)benzoyl]-1,2,3,4-tetrahydroquinoxalin-1-yl}methyl)benzoate (CAS 317822-33-6)
- 1-(Propan-2-yl)-1H-imidazole-5-carbaldehyde hydrochloride (CAS 1426688-38-1)
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- Benzyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 130753-13-8)
- 5-Bromo-2-methylbenzo[b]thiophene-1,1-dioxide (CAS 63166-90-5)
- 7-Hydroxy Propranolol HCl (CAS 76275-67-7)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
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