6-Chloro-N-(3-((2-methylbenzyl)thio)-1H-1,2,4-triazol-5-yl)nicotinamide CAS 866011-04-3
| CAS No. | 866011-04-3 |
| Molecular Formula | C16H14ClN5OS |
| Molecular Weight | 359.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-N-(3-((2-methylbenzyl)thio)-1H-1,2,4-triazol-5-yl)nicotinamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Chloro-N-(3-((2-methylbenzyl)thio)-1H-1,2,4-triazol-5-yl)nicotinamide (CAS 866011-04-3) is a high-purity analytical reference standard with the molecular formula C16H14ClN5OS and a molecular weight of 359.83 g/mol.
The molecular framework of 6-Chloro-N-(3-((2-methylbenzyl)thio)-1H-1,2,4-triazol-5-yl)nicotinamide (C16H14ClN5OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-N-(3-((2-methylbenzyl)thio)-1H-1,2,4-triazol-5-yl)nicotinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN5OS |
| Molecular Weight | 359.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-N-(2-((3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)phenyl)thiophene-2-carboxamide (CAS 1797962-38-9)
- (10R)-2-chloro-10-methyl-4-(1-(methylsulfonyl)cyclopropyl)-6a,7,9,10-tetrahydro-6H-[1,4]oxazino[4,3-d]pyrimido[5,4-b][1,4]oxazine (CAS 2161304-95-4)
- 1-{1-[(2-chloro-4-fluorophenyl)methyl]piperidin-4-yl}-2,3-dihydro-1h-1,3-benzodiazol-2-one (CAS 909682-49-1)
- Benzyl (4-(3-chloro-5-ethynyl-4-fluorophenyl)butyl)carbamate (CAS 1427039-32-4)
- (E)-2-(2-chloro-6-fluorobenzyl)-5-(dimethylamino)-1-phenylpent-4-ene-1,3-dione (CAS 900015-47-6)
- (3-Chloro-4-methylphenyl)(4-(4-nitrophenyl)piperazin-1-yl)methanone (CAS 431996-53-1)
- (E)-6-Chloro-3-(pyridin-2-yl)-2-styrylquinazolin-4(3H)-one (CAS 708212-97-9)
- 1-{[6-Chloro-2-(furan-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 904818-06-0)
Recommended Standards
- 5-(4-Chlorophenyl)-3-tosylpyridin-2(1H)-one (CAS 400089-32-9)
- Methyl 2-((3-(4-chlorophenyl)-4-imino-3,4-dihydroquinazolin-2-yl)thio)acetate (CAS 478039-25-7)
- 4-(4-Chlorophenyl)-5-(4-methylbenzenesulfonyl)pyrimidin-2-amine (CAS 338417-79-1)
- n-(3-(Benzo[d]thiazol-2-ylamino)-3-oxopropyl)-2-chlorobenzamide (CAS 783318-35-4)
- 2-Chloro-4-(cyclopentyloxy)-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1618663-33-4)
- (2-Aminonaphthalen-1-yl)boronic acid (CAS 1621964-95-1)
- Methyl chlorosulfonate (CAS 812-01-1)
- 5-Methoxyquinoxalin-2-amine (CAS 659729-75-6)
- (3R)-3-(4-hydroxy-1-oxo-isoindolin-2-yl)piperidine-2,6-dione (CAS 2414414-22-3)
- Isoquinolin-3-ylmethanol (CAS 76884-34-9)
- 2-(2-cyanophenoxy)-3-methylbutanoic acid (CAS 1016502-71-8)
- (1s,3s,5s,6s)-6-(Trifluoromethyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid hydrochloride (CAS 1212424-47-9)
- (3-(Difluoromethyl)-2-fluoro-6-methylpyridin-4-yl)methanamine (CAS 1805984-15-9)
- Semaglutide impurity 76 (CAS CATO-C4X-222676)
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