2-Amino-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-[1,2,4]triazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one CAS 866018-19-1
| CAS No. | 866018-19-1 |
| Molecular Formula | C18H18N6O3 |
| Molecular Weight | 366.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Amino-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-[1,2,4]triazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Amino-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-[1,2,4]triazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one (CAS 866018-19-1), molecular formula C18H18N6O3 and molecular weight 366.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Amino-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-[1,2,4]triazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one (C18H18N6O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18N6O3 |
| Molecular Weight | 366.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
Related Amino Standards
- 2-Amino-5-(3-(4-nitrophenoxy)propyl)-6-phenylpyrimidin-4(3H)-one (CAS 14937-56-5)
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- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-2,6-difluorobenzamide (CAS 102587-96-2)
- 1-[3-Amino-6-(3-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]ethan-1-one (CAS 625377-34-6)
- 2-Amino-8-(pyren-1-ylamino)-1H-purin-6(7H)-one (CAS 97228-93-8)
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Recommended Standards
- 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-5-nitrobenzonitrile (CAS 924072-98-0)
- 3-((2-Fluoro-5-nitrophenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile (CAS 333414-97-4)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-azidobutanoic acid (CAS 934502-72-4)
- 3-(2-Hydroxyphenyl)-1-methyl-4,6-dioxo-5-phenyloctahydropyrrolo[3,4-c]pyrrole-1-carboxylic acid (CAS 496923-35-4)
- 3-Methyl-1-(pyridin-3-yl)butan-1-one (CAS 82465-52-9)
- 4-(5-Ethoxypyrimidin-2-yl)phenol (CAS 121554-73-2)
- 4-chloro-2-(chloromethyl)-6-fluoropyridine (CAS 1393565-82-6)
- (1-(5-Methylpyridin-2-yl)piperidin-3-yl)methanol (CAS 939986-72-8)
- 6-Bromo-2,3-dihydrofuro[2,3-b]quinoline (CAS 158725-34-9)
- 4-Bromo-2-fluoro-N-isopropylbenzamide (CAS 877383-76-1)
- 4-(4-Chlorophenyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 303996-81-8)
- 2-Chloro-n-(1-propyl-1h-pyrazol-5-yl)acetamide (CAS 1209931-68-9)
- 5,6,7,8-Tetrahydro-5,8-methanoquinoxaline-2-carboxylic acid (CAS 1706452-01-8)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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