3-Chloro-2,2-dimethyl-N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)propanamide CAS 866018-65-7
| CAS No. | 866018-65-7 |
| Molecular Formula | C17H18ClF3N2OS |
| Molecular Weight | 390.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 3-Chloro-2,2-dimethyl-N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)propanamide (CAS 866018-65-7), a certified reference material (molecular formula C17H18ClF3N2OS, MW 390.85 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-2,2-dimethyl-N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)propanamide (C17H18ClF3N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18ClF3N2OS |
| Molecular Weight | 390.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 5-Bromo-1-(2,3-dibromopropyl)pyrimidine-2,4(1H,3H)-dione (CAS 195508-05-5)
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- 2,4,6-Tribromo-3,5-dimethoxyphenol (CAS 121869-55-4)
- Tert-butyl 4-(5-chloro-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1062070-07-8)
- 1,3-Dihydroisobenzofuran-5-boronic Acid Pinacol Ester (CAS 1352037-60-5)
- [(4-chlorophenyl)(pyridin-3-yl)methyl](ethyl)amine (CAS 1153125-91-7)
- 5-(2-Bromophenoxy)-1-methyl-4-nitro-1h-imidazole (CAS 1030819-27-2)
- (R)-((1S,2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol hydrobromide xhydrate (CAS 207386-86-5)
- 2-(Bromomethyl)-5-chlorobenzofuran (CAS 139313-90-9)
- 2-Fluoro-4-(methylsulfonyl)benzyl bromide (CAS 1401796-84-6)
- N-(m-tolyl)benzamide (CAS 582-77-4)
- (S)-1-(4-Bromo-2-fluorophenyl)ethanamine hydrochloride (CAS 1311254-85-9)
- 1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (CAS 4080-31-3)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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