6,8-Dibromo-3-(4-methylbenzenesulfonyl)quinolin-2-amine CAS 866019-18-3
| CAS No. | 866019-18-3 |
| Molecular Formula | C16H12Br2N2O2S |
| Molecular Weight | 456.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6,8-Dibromo-3-(4-methylbenzenesulfonyl)quinolin-2-amine (CAS 866019-18-3) is a high-purity analytical reference standard with the molecular formula C16H12Br2N2O2S and a molecular weight of 456.15 g/mol.
6,8-Dibromo-3-(4-methylbenzenesulfonyl)quinolin-2-amine (C16H12Br2N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6,8-Dibromo-3-(4-methylbenzenesulfonyl)quinolin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12Br2N2O2S |
| Molecular Weight | 456.15 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dibromo Standards
- 2,4-Dibromo-6-(trimethylsilyl)phenyl trifluoromethanesulfonate (CAS 1449472-57-4)
- 6,8-Dibromo-3-(o-tolylsulfonyl)quinolin-2-amine (CAS 861210-88-0)
- (4,5-Dibromo-6-oxopyridazin-1(6H)-yl)methyl 3-(trifluoromethyl)benzoate (CAS 439108-09-5)
- 2,2'-Dibromo-3,3',4,4',5,5',6,6'-octafluoro-1,1'-biphenyl (CAS 5576-19-2)
- Dibromo(2,2':6',2''-terpyridyl)copper (CAS 25971-38-4)
- (4,5-Dibromo-6-oxo-1,6-dihydropyridazin-1-yl)methyl 3,4-dichlorobenzoate (CAS 439108-06-2)
- 2-(2,3-Dibromo-6-ethoxy-4-formylphenoxy)-N-phenylacetamide (CAS 445002-46-0)
- 2,4-Dibromo-6-methyl-3-(propan-2-yl)phenyl 3-nitrobenzoate (CAS 439094-36-7)
Recommended Standards
- 5-Chloro-N-(4-chlorobenzyl)-1-(2,4-dichlorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242472-00-0)
- N-(5,7-Dibromoquinolin-8-yl)-4-methylbenzenesulfonamide (CAS 21868-75-7)
- Dimethyl (3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)phosphonate (CAS 61726-44-1)
- Ziprasidone Impurity 70 (CAS CATO-C4X-124070)
- 3-(p-Tolyl)-1H-isochromen-1-one (CAS 62827-73-0)
- 4-Cyclopropoxy-N,N-dimethyl-6-(methylthio)pyridin-3-amine (CAS 1243452-23-4)
- 2-(2-Chloro-8-isopropylquinolin-3-yl)acetonitrile (CAS 1017191-94-4)
- Pyrazolo[1,5-a]pyrimidine-6-carbaldehyde (CAS 933754-42-8)
- 3-(2-Oxopyrrolidin-1-yl)benzohydrazide (CAS 420097-54-7)
- 2-(Quinolin-2-yl)morpholine (CAS 1341035-86-6)
- 2-Hydroxy-4-(2,2,2-trifluoroethyl)benzoic acid (CAS 1393561-95-9)
- N1-(2-fluorobenzyl)-3-chloro-2,2-dimethylpropanamide (CAS 243963-36-2)
- Ethyl 2-(2,4-dimethylphenyl)acetate (CAS 105337-16-4)
- [Ser39-OH] Tirzepatide (CAS CATO-C4X-324041)
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