N-(3-(4-benzylpiperazin-1-yl)-1-(4-ethylphenyl)-3-oxopropyl)-2,2,2-trifluoroacetamide CAS 866019-23-0
| CAS No. | 866019-23-0 |
| Molecular Formula | C24H28F3N3O2 |
| Molecular Weight | 447.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(3-(4-benzylpiperazin-1-yl)-1-(4-ethylphenyl)-3-oxopropyl)-2,2,2-trifluoroacetamide (CAS 866019-23-0), molecular formula C24H28F3N3O2 and molecular weight 447.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3-(4-benzylpiperazin-1-yl)-1-(4-ethylphenyl)-3-oxopropyl)-2,2,2-trifluoroacetamide (C24H28F3N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H28F3N3O2 |
| Molecular Weight | 447.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 3-((4-Benzylpiperazin-1-yl)methyl)-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine (CAS 861212-41-1)
- N-(4-(4-benzylpiperazin-1-yl)phenyl)-2,4-dichlorobenzamide (CAS 303151-02-2)
- N-(4-(4-benzylpiperazin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 303150-98-3)
- 11-(4-Benzylpiperazin-1-yl)-4-methyl-8-thia-12-azatetracyclo[8.8.0.0^{2,7}.0^{13,18}]octadeca-1(18),2,4,6,10,12,14,16-octaene (CAS 866136-66-5)
- 1-(4-Benzylpiperazin-1-yl)-3-(1,3-dioxoisoindolin-2-yl)propan-2-yl methanesulfonate (CAS 186348-46-9)
- 1226429-03-3 2-(4-benzylpiperazin-1-yl)-7-(4-chlorophenyl)thieno[3,2-d]pyrimidin-4(3H)-one KS-00003JRW (CAS 1226429-03-3)
- (4-Benzylpiperazin-1-yl)(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)methanone (CAS 956170-39-1)
- (Z)-[2-(4-Benzylpiperazin-1-yl)-1-phenylethylidene][(4-chlorophenyl)methoxy]amine (CAS 250714-06-8)
Recommended Standards
- L-Phenylalanyl-N-(di-1H-imidazoL-2-ylmethyl)-L-histidinamide (CAS 666746-74-3)
- Oxaline (CAS 55623-37-5)
- Ethyl 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(((6-ethoxybenzo[d]thiazol-2-yl)thio)methyl)-1H-1,2,3-triazole-4-carboxylate (CAS 312499-48-2)
- Siponimod impurity 21 (CAS CATO-C4X-247221)
- Diethyl 2-methyl-3-oxopyrrolidine-1,2-dicarboxylate (CAS 61334-21-2)
- 1,4-Diiodo-2,5-dioctylbenzene (CAS 171569-01-0)
- rac 2-Palmitoyl-3-chloropropanediol (CAS 20618-92-2)
- 3,5-Dichloro-3-(4-methylpiperazinomethyl) benzophenone (CAS 898789-29-2)
- 1-Hydroxydecahydronaphthalene-2-carboxylic acid (CAS 861354-05-4)
- tert-butyl (3S)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate (CAS 2567925-74-8)
- 6-Methylchromane-3-carboxylic acid (CAS 944899-30-3)
- 3-Bromophenylboronic acid MIDA ester (CAS 943552-25-8)
- 3-(((3-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477860-20-1)
- Endo-[Glu]31-Liraglutide (CAS CATO-C4X-199234)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com