Ethyl 1-(3-(4-ethylphenyl)-3-(2,2,2-trifluoroacetamido)propanoyl)piperidine-4-carboxylate CAS 866019-27-4
| CAS No. | 866019-27-4 |
| Molecular Formula | C21H27F3N2O4 |
| Molecular Weight | 428.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 1-(3-(4-ethylphenyl)-3-(2,2,2-trifluoroacetamido)propanoyl)piperidine-4-carboxylate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 1-(3-(4-ethylphenyl)-3-(2,2,2-trifluoroacetamido)propanoyl)piperidine-4-carboxylate (CAS 866019-27-4), molecular formula C21H27F3N2O4 and molecular weight 428.45 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 1-(3-(4-ethylphenyl)-3-(2,2,2-trifluoroacetamido)propanoyl)piperidine-4-carboxylate (C21H27F3N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 1-(3-(4-ethylphenyl)-3-(2,2,2-trifluoroacetamido)propanoyl)piperidine-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H27F3N2O4 |
| Molecular Weight | 428.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
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Recommended Standards
- 4-(4-(Tert-butyl)benzoyl)-N-(3-(trifluoromethyl)benzyl)-1H-pyrrole-2-carboxamide (CAS 439111-61-2)
- Iloperidone Metabolites P95 (CAS 475110-48-6)
- 2-((4-((Difluoromethyl)thio)phenyl)amino)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide (CAS 325730-45-8)
- N-(2,6-Diethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 339027-88-2)
- (2-Hydroxy-1,4-phenylene)dimethanol (CAS 42934-01-0)
- 8-Hydroxy-2-methylquinoline-7-carboxylic acid hydrate (CAS 856451-85-9)
- 2-(Cyclopropylamino)-2-methylpropanamide (CAS 1170701-10-6)
- Isavuconazole Impurity 225 (CAS CATO-C4X-1236225)
- 2-Tri-n-butylstannylpyridine (CAS 17997-47-6)
- O1-tert-butyl O3-methyl 7-oxo-4H-pyrazolo[4,3-d]pyrimidine-1,3-dicarboxylate (CAS 2839502-25-7)
- 4-((5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol (CAS 727385-51-5)
- 4-Fluoro-1,3-dimethyl-1H-pyrazole-5-carboxylic acid (CAS 1936196-92-7)
- 5-Bromo-7-methoxychroman-4-one (CAS 1344894-65-0)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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