4-(4-Chloro-3-(trifluoromethyl)benzyl)thiomorpholine 1,1-dioxide CAS 866020-48-6
| CAS No. | 866020-48-6 |
| Molecular Formula | C12H13ClF3NO2S |
| Molecular Weight | 327.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 327.75 g/mol gives 4-(4-Chloro-3-(trifluoromethyl)benzyl)thiomorpholine 1,1-dioxide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(4-Chloro-3-(trifluoromethyl)benzyl)thiomorpholine 1,1-dioxide (CAS 866020-48-6) is a high-purity analytical reference standard with the molecular formula C12H13ClF3NO2S and a molecular weight of 327.75 g/mol.
The molecular framework of 4-(4-Chloro-3-(trifluoromethyl)benzyl)thiomorpholine 1,1-dioxide (C12H13ClF3NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13ClF3NO2S |
| Molecular Weight | 327.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 1-(2-Chlorobenzenesulfonyl)-4-(trifluoromethyl)piperidine (CAS 911643-37-3)
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- N-(2-Chlorophenyl)-2-((2-methylquinazolin-4-yl)oxy)acetamide (CAS 1029764-08-6)
- 2-{[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]-methoxy}benzaldehyde (CAS 1048917-33-4)
- 2-Azetidinone, 3-butyl-1-(phenylmethoxy)-, (3R)- 676127-84-7 CTK1H7245 (CAS 676127-84-7)
- 5-Bromo-N1-phenylbenzene-1,2-diamine (CAS 343952-87-4)
- tert-Butyl ((phenylsulfonyl)methyl)carbamate (CAS 1242161-32-5)
- 1-Amino-4-benzylpiperazine (CAS 39139-52-1)
- 1-(5-Chloro-2-hydroxyphenyl)butane-1,3-dione (CAS 65897-66-7)
- H-Nle-NH2.HCl (CAS 94787-97-0)
- 2-(3-Bromo-5-cyano-2-methoxyphenyl)acetic acid (CAS 1805528-68-0)
- 1-(6-o-Tolylpyridin-3-yl)-ethanone (CAS 2088942-18-9)
- 2-Chloro-N-(4-chlorophenyl)-N-methylquinazolin-4-amine (CAS 827030-35-3)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
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