2,4-Difluoro-3-(hydroxymethyl)phenol CAS 866028-20-8
| CAS No. | 866028-20-8 |
| Molecular Formula | C7H6F2O2 |
| Molecular Weight | 160.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2,4-Difluoro-3-(hydroxymethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2,4-Difluoro-3-(hydroxymethyl)phenol (CAS 866028-20-8), molecular formula C7H6F2O2 and molecular weight 160.12 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H6F2O2, 2,4-Difluoro-3-(hydroxymethyl)phenol contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 160.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6F2O2 |
| Molecular Weight | 160.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,5-Difluoro-4-methoxyphenol (CAS 1024068-86-7)
- 2,2-Difluoro-1-(1-methyl-1H-pyrazol-4-yl)ethan-1-one (CAS 1174839-82-7)
- 2,4-Difluoro-6-methoxyphenol (CAS 1193392-90-3)
- 3,5-Difluoro-2-(hydroxymethyl)phenol (CAS 136516-72-8)
- 4,4-Difluoro-1,4,5,7-tetrahydropyrano[3,4-c]pyrazole (CAS 1391732-92-5)
- 3,4-Difluoro-5-methoxyphenol (CAS 1394915-77-5)
- 3,5-Difluoro-2-methoxyphenol (CAS 152434-94-1)
- 3,4-Difluoro-2-methoxyphenol (CAS 158626-90-5)
Recommended Standards
- 2,3-Difluoro-6-(hydroxymethyl)phenol (CAS 936328-58-4)
- 2,4-Difluoro-3-methoxyphenol (CAS 886499-27-0)
- 2,3-Difluoro-5-(hydroxymethyl)phenol (CAS 887585-06-0)
- 2,6-Difluoro-3-methoxyphenol (CAS 886498-60-8)
- (S)-2,2,2-trifluoro-1-(tetrahydro-2H-pyran-4-yl)ethan-1-ol (CAS 1568225-06-8)
- 898760-62-8 (3-Chloro-5-fluorophenyl)[4-(1,3-dioxolan-2-yl)phenyl]methanone DTXSID80645130 (CAS 898760-62-8)
- Ethyl 2-amino-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate (CAS 1211532-57-8)
- Pioglitazone impurity 51 (CAS CATO-C4X-138351)
- 5-(Methylaminomethyl)-2-thiouridine (CAS 32860-54-1)
- 4-Octylbenzyl Chloride (CAS 40016-26-0)
- Benzoic Acid 3,4-Bis (Trifluoro Ethoxy) (CAS 35480-54-7)
- TERRITREM B (CAS 70407-20-4)
- 1-(2-Chloro-4-pyrimidinyl)ethanol (CAS 1312535-79-7)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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