N-{2,4-dichloro-5-[(3-fluorophenyl)methoxy]phenyl}-3-methylbenzamide CAS 866039-27-2
| CAS No. | 866039-27-2 |
| Molecular Formula | C21H16Cl2FNO2 |
| Molecular Weight | 404.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-{2,4-dichloro-5-[(3-fluorophenyl)methoxy]phenyl}-3-methylbenzamide (CAS 866039-27-2) is a high-purity analytical reference standard with the molecular formula C21H16Cl2FNO2 and a molecular weight of 404.26 g/mol.
The molecular framework of N-{2,4-dichloro-5-[(3-fluorophenyl)methoxy]phenyl}-3-methylbenzamide (C21H16Cl2FNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-{2,4-dichloro-5-[(3-fluorophenyl)methoxy]phenyl}-3-methylbenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H16Cl2FNO2 |
| Molecular Weight | 404.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 2,4-Dichloro-5-{[2-(4-methoxyphenyl)ethyl]sulfamoyl}benzoic acid (CAS 743451-78-7)
- 2-[N-(2,4-Dichloro-5-methoxyphenyl)4-methylbenzenesulfonamido]acetic acid (CAS 338961-17-4)
- Dichloro(4-methoxy-1,2-benzenediamine)platinum (CAS 72595-97-2)
- 3-(5,6-Dichloro-1-(2-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 338774-08-6)
- 3-{5,6-dichloro-1-[(3-chlorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 338774-22-4)
- 5-(5,6-Dichloro-1-(2-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 338774-04-2)
- (2Z)-2,3-Dichloro-3-{[(2-chlorophenyl)methyl]sulfanyl}-N-(6-methoxypyridin-3-yl)prop-2-enamide (CAS 337922-06-2)
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Recommended Standards
- N-((ethylcarbamoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338395-38-3)
- tert-Butyl (3-cyano-4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-7-fluorobenzo[b]thiophen-2-yl)carbamate (CAS 2649788-80-5)
- 2-[(2-Chloro-6-fluorophenyl)methyl]-4-[(1E)-{[(4-chlorophenyl)methyl]imino}methyl]benzene-1,3-diol (CAS 339017-56-0)
- 2,4-Bis(benzyloxy)-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)pyrimidine (CAS 1072944-91-2)
- Propyl 6-aminopyridazine-3-carboxylate (CAS 98594-47-9)
- tert-Butyl N-(1-methylpyrazol-3-yl)carbamate (CAS 128883-86-3)
- Ethyl 3-amino-4-[4-(2-hydroxyethyl)-1-piperazinyl]benzoate (CAS 1220019-73-7)
- Atrasentan Impurity 12 (CAS 1098784-86-1)
- Fasudil Impurity 14 (CAS CATO-C4X-136514)
- 2-Chloro-5-methyl-isonicotinonitrile (CAS 924651-92-3)
- Ethyl 6-methyl-1H-indole-2-carboxylate (CAS 16732-81-3)
- (2-(Trifluoromethyl)oxetan-2-yl)methanamine hydrochloride (CAS 2839143-16-5)
- (4-(Pyrimidin-2-yl)thiophen-2-yl)boronic acid (CAS 2225179-82-6)
- Peptide 440 (CAS CATO-CPTD788440)
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