1-((4-Fluorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one CAS 866039-76-1
| CAS No. | 866039-76-1 |
| Molecular Formula | C18H17FN2O4S |
| Molecular Weight | 376.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-((4-Fluorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-((4-Fluorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 866039-76-1), a certified reference material (molecular formula C18H17FN2O4S, MW 376.40 g/mol) for analytical method development and quality control.
1-((4-Fluorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (C18H17FN2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-((4-Fluorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17FN2O4S |
| Molecular Weight | 376.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 1-(2-Fluorophenyl)-4-{1H,2H-naphtho[2,1-b]furan-2-carbonyl}piperazine (CAS 439111-16-7)
- 434907-99-0 6-{[(4-Fluorophenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid MFCD14282105 (CAS 434907-99-0)
- Ethyl 4-[4-(2-fluorophenyl)piperazino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate (CAS 339019-52-2)
- N-(1-((4-Fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)butyramide (CAS 941971-60-4)
- N-(2-Fluorophenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide (CAS 683791-90-4)
- 2-(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)benzo[d]thiazole (CAS 605628-16-8)
- 1-(4-Fluorophenyl)-3-((2,3,4,5,6-pentamethylbenzyl)sulfonyl)propan-1-one (CAS 868255-95-2)
- N-[(4-Fluorophenyl)methyl]-2-(pyridin-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 865660-43-1)
Recommended Standards
- (S)-2-(1-Aminoethyl)-7-fluoro-1-(4-fluorophenyl)-3-phenyl-4H-quinolizin-4-one (CAS 2101519-13-3)
- 1-(Tert-butyl) 3-ethyl 4-((phenoxycarbonyl)amino)-2,5-dihydro-1H-pyrrole-1,3-dicarboxylate (CAS 2387601-84-3)
- (S)-2-((S)-1-((Benzyloxy)carbonyl)-5-oxopyrrolidine-2-carboxamido)-4-methylpentanoic acid (CAS 71034-37-2)
- 2-(((1H-benzo[d]imidazol-2-yl)methyl)thio)-6-ethyl-5-methyl-4-(trifluoromethyl)nicotinonitrile (CAS 939888-46-7)
- 5-({[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]amino}methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 497060-06-7)
- 2-(Difluoromethyl)-3,6-dihydroxypyridine-4-sulfonamide (CAS 1804715-52-3)
- 3-Amino-4-((tert-butoxycarbonyl)amino)butanoic acid (CAS 773126-09-3)
- 4-Bromo-3-methylbenzenesulfonamide (CAS 879487-75-9)
- 3-Phenyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 836633-05-7)
- Vericiguat Impurity 37 (CAS CATO-C4X-289637)
- 5-Amino-1H-imidazole-2,4-dicarbonitrile (CAS 909073-67-2)
- 2-(Benzyloxy)isonicotinic Acid (CAS 467236-25-5)
- 2,2-Dimethoxy-1-(3-(trimethoxysilyl)propyl)-1,2-azasilolidine (CAS 109084-60-8)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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