Lansoprazole Impurity 46 CAS 86604-77-5
| CAS No. | 86604-77-5 |
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lansoprazole Impurity 46 (CAS 86604-77-5, C8H11NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lansoprazole Impurity 46 (C8H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 153.18 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lansoprazole Impurity 46 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 1 |
Related Lansoprazole Standards
- Lansoprazole Impurity 11 (CAS 1329838-16-5)
- Lansoprazole EP Impurity E (CAS 583-39-1)
- Lansoprazole impurity 75 (CAS 1805648-51-4)
- Lansoprazole Impurity 48 (CAS 27231-33-0)
- Lansoprazole Impurity 41 (CAS 7152-24-1)
- Lansoprazole Impurity 19 (CAS 4377-43-9)
- Lansoprazole Impurity 10027-0322 (CAS 1551185-85-3)
- Lansoprazole Impurity 35 (CAS 1797131-12-4)
Recommended Standards
- Esomeprazole Impurity 94 (CAS 91219-89-5)
- Avanafil Impurity 81 (CAS 89702-89-6)
- Vildagliptin Impurity 9 (CAS CATO-C4X-11009)
- Ilaprazole impurity 204 (CAS 1379034-97-5)
- Bosutinib Impurity 14 (CAS CATO-C4X-184714)
- Tofacitinib Impurity 130 (CAS 2564-07-0)
- Fenoterol Impurity 8 HBr (CAS CATO-C4X-20778)
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- H-α-Difluoro-Me-DL-Orn-OH · HCl · H2O (CAS 96020-91-6)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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