4-(4-Bromophenyl)-3-(3,5-dichlorophenyl)-1-(pyridin-3-yl)butan-2-ol CAS 866043-51-8
| CAS No. | 866043-51-8 |
| Molecular Formula | C21H18BrCl2NO |
| Molecular Weight | 451.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Bromophenyl)-3-(3,5-dichlorophenyl)-1-(pyridin-3-yl)butan-2-ol.
CATO supplies 4-(4-Bromophenyl)-3-(3,5-dichlorophenyl)-1-(pyridin-3-yl)butan-2-ol (CAS 866043-51-8), a certified reference material (molecular formula C21H18BrCl2NO, MW 451.18 g/mol) for analytical method development and quality control.
4-(4-Bromophenyl)-3-(3,5-dichlorophenyl)-1-(pyridin-3-yl)butan-2-ol (C21H18BrCl2NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18BrCl2NO |
| Molecular Weight | 451.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenyl Standards
- N-{2-[(4-bromophenyl)sulfanyl]ethyl}-2-[(2,3-dichlorophenyl)sulfanyl]acetamide (CAS 337923-61-2)
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- 3-(4-(4-Bromophenyl)-5-((2,5-dimethylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 677310-89-3)
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Recommended Standards
- ((2S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 66004-77-1)
- 4-Bromo-N-(4-((3,4-dichlorobenzyl)oxy)benzyl)-3-methylaniline (CAS 329928-96-3)
- 9-(2,4-Dichlorophenyl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine (CAS 338773-44-7)
- 6-(2,6-Dichlorobenzyl)-2-(3,4-dichlorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine (CAS 477858-94-9)
- 1-Benzyl-4-chloro-1H-pyrazole (CAS 50877-40-2)
- 4-{[3-(methylamino)propyl]amino}butanoic acid dihydrochloride (CAS 1423028-02-7)
- 3,9-Dimethyl-7-pentyl-1,4-dihydro-[1,2,4]triazino[3,4-f]purine-6,8(7H,9H)-dione (CAS 922454-40-8)
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- Ethyl N-(2-aminoethyl)-N-methylglycinate (CAS 690953-90-3)
- n-(2-Aminoethyl)-4-fluoro-n-methylbenzenesulfonamide (CAS 1018536-49-6)
- Methyl (S)-Pyrrolidine-3-carboxylate Hydrochloride (CAS 1099646-61-3)
- Rimegepant Impurity 93 (CAS CATO-C4X-248793)
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