2-Hydroxy-3-(piperidin-1-yl)-1,3-di-p-tolylpropan-1-one CAS 866049-62-9
| CAS No. | 866049-62-9 |
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Hydroxy-3-(piperidin-1-yl)-1,3-di-p-tolylpropan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Hydroxy-3-(piperidin-1-yl)-1,3-di-p-tolylpropan-1-one (CAS 866049-62-9) is a high-purity analytical reference standard with the molecular formula C22H27NO2 and a molecular weight of 337.46 g/mol.
The molecular framework of 2-Hydroxy-3-(piperidin-1-yl)-1,3-di-p-tolylpropan-1-one (C22H27NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1-Phenyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine (CAS 1036605-83-0)
- tert-butyl N-[4-(bromomethyl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]carbamate (CAS 1803272-45-8)
- 4-Hydroxycyclohexyl 4-methylbenzenesulfonate (CAS 92121-36-3)
- 9-Chloro-3-methyl-5-nitroacridine (CAS 255713-06-5)
- trans-2-[Benzyl(methyl)amino]cyclohexanol (CAS 109433-73-0)
- 1-(Benzenesulfonyl)-3-[(4-chlorophenyl)sulfanyl]propan-2-ol (CAS 338409-57-7)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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