Ethyl 4-chloro-1-(4-chlorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate CAS 866050-41-1
| CAS No. | 866050-41-1 |
| Molecular Formula | C16H13Cl2N3O2 |
| Molecular Weight | 350.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 350.20 g/mol gives Ethyl 4-chloro-1-(4-chlorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 4-chloro-1-(4-chlorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 866050-41-1), molecular formula C16H13Cl2N3O2 and molecular weight 350.20 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 4-chloro-1-(4-chlorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (C16H13Cl2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 350.20 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl2N3O2 |
| Molecular Weight | 350.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 1-(4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(2-chlorophenyl)urea (CAS 649665-31-6)
- 2-Chloro-1-{1-[4-chloro-3-(trifluoromethyl)phenyl]-2,5-dimethyl-1h-pyrrol-3-yl}ethan-1-one (CAS 329266-67-3)
- 1-(5-Chloro-2-methylphenyl)-4-(2-chloropyridine-3-carbonyl)piperazine (CAS 1024496-60-3)
- 7-Chloro-2-(5-ethyl-2-thienyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160256-86-9)
- (2-Chloro-6-(ethoxycarbonyl)phenyl)zinc pivalate ( 0.85 mmol/g) (CAS 1643794-44-8)
- 3-Chloro-N-(3-chloro-4-methylphenyl)-6-methylbenzo[b]thiophene-2-carboxamide (CAS 332381-94-9)
- 7-Chloro-N-(2-((4-chlorophenyl)thio)ethyl)quinazolin-4-amine (CAS 477862-06-9)
- Chloro Efavirenz(Mixture of Diastereomers) (CAS 1322625-98-8)
Recommended Standards
- 5-[(3,4-Dichlorophenoxy)methyl]-3-(4-methoxyphenyl)-1,2-oxazole (CAS 478066-53-4)
- Methyl 5-cyano-6-[(2,4-dichlorobenzyl)amino]-2-methylnicotinate (CAS 306979-99-7)
- 4-[7-(3,4-Dichlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]morpholine (CAS 338403-62-6)
- N-(1H-Benzo[d]imidazol-2-yl)-3,5-dichloro-2-ethoxybenzamide (CAS 81268-69-1)
- Ethyl 2-sulfamoylpropanoate (CAS 55897-05-7)
- Tert-butyln-tert-butoxycarbonyl-N-[(2,6-dichloropyrimidin-4-yl)methyl]carbamate (CAS 1984827-51-1)
- 5-(5-Bromofuran-2-yl)isoxazol-3-amine (CAS 91678-90-9)
- cis-tert-Butyl hexahydro-1H-pyrrolo[2,3-c]pyridine-6(2H)-carboxylate (CAS 1286755-20-1)
- 2-Methyl-2H-benzo[d][1,2,3]triazole-4-carbaldehyde (CAS 1936022-13-7)
- (S)-2-((2S,4R)-4-acetamido-2-(4-chlorobenzyl)piperidin-1-yl)-2-oxo-1-phenylethyl acetate (CAS 177770-52-4)
- 2-Amino-n-[1-(2,5-dimethylthiophen-3-yl)ethyl]butanamide hydrochloride (CAS 1423027-45-5)
- Methyl 2-(3,5-dimethyl-1H-pyrrol-2-yl)-2-oxoacetate (CAS 371786-24-2)
- Riluzole Impurity 5 (CAS 235101-36-7)
- Insulin B (22-25) (CAS 34367-73-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com