N-(2-methoxybenzyl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide CAS 866051-29-8
| CAS No. | 866051-29-8 |
| Molecular Formula | C22H18F3NO2 |
| Molecular Weight | 385.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 385.38 g/mol gives N-(2-methoxybenzyl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(2-methoxybenzyl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide (CAS 866051-29-8), molecular formula C22H18F3NO2 and molecular weight 385.38 g/mol, is a CATO reference standard with documented purity and traceability.
N-(2-methoxybenzyl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide (C22H18F3NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18F3NO2 |
| Molecular Weight | 385.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 4-Methoxybenzyl (1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)carbamate (CAS 866143-89-7)
- 3-((4-Methoxybenzyl)oxy)-N-(4-nitrophenyl)thiophene-2-carboxamide (CAS 339098-27-0)
- 2-(((4-Methoxybenzyl)oxy)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole (CAS 2489244-72-4)
- 2-((4-Methoxybenzyl)thio)-1-methyl-4,5-diphenyl-1H-imidazole (CAS 339277-67-7)
- 3-Ethyl-2-((3-methoxybenzyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 578754-04-8)
- 4-(4-Methoxybenzyl)-8-(4-nitrophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane (CAS 303151-64-6)
- 3-(3-(5-((4-Methoxybenzyl)oxy)pyridin-2-yl)-1,2,4-oxadiazol-5-yl)-2,2-dimethylpropanoic acid (CAS 917911-01-4)
- 6-(3-Methoxybenzyl)-4-methyl-2-(methylsulfinyl)-4H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5(6H)-one (CAS 1221186-52-2)
Recommended Standards
- Methyl 2-(allyl((benzyloxy)carbonyl)amino)-2-(trifluoromethyl)hex-5-enoate (CAS 397844-32-5)
- N'-(Naphthalen-1-ylmethylene)-3-(3-nitrophenyl)-1H-pyrazole-5-carbohydrazide (CAS 302918-28-1)
- 9-(2-Bromoethyl)-2,7-di-tert-butyl-9H-fluorene (CAS 710280-54-9)
- N,N-Bis(diphenylphosphino)amine (CAS 2960-37-4)
- N-(4-(Pyridin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide (CAS 23655-67-6)
- 2-(2,2,2-Trifluoroethoxy)pyrimidine-5-boronic acid (CAS 1401163-85-6)
- 4-(4'-Hydroxyphenyl)-2-butanone-d5 (CAS 182219-43-8)
- 6-Methoxy-7-Methyl-Quinoline (CAS 467219-83-6)
- (R)-Benzyl 2-(Trifluoromethylsulfonyloxy)propionate (CAS 93836-43-2)
- 3-(4-Methoxy-3-methylphenyl)-2-methylpropanoic acid (CAS 1507176-56-8)
- 4-methoxycyclohexanecarbaldehyde (CAS 120552-57-0)
- Ribavirin Impurity 30-d6 (CAS 175733-29-6)
- rac-[(2R,3R)-1-cyclopropyl-2-(1-methyl-1H-imidazol-5-yl)piperidin-3-yl]methanol (CAS 1969288-14-9)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com