2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid CAS 866108-77-2

Purity 97%+In StockPharmaceutical Standards
CAS No.866108-77-2
Molecular FormulaC14H10F2O2
Molecular Weight248.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid CAS 866108-77-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid.

2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid (CAS 866108-77-2), molecular formula C14H10F2O2 and molecular weight 248.22 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid (C14H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10F2O2
Molecular Weight248.22 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

Related Difluoro Standards

Recommended Standards

Why CATO?