(2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide CAS 866131-00-2
| CAS No. | 866131-00-2 |
| Molecular Formula | C17H10F7N3O2 |
| Molecular Weight | 421.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide (CAS 866131-00-2), molecular formula C17H10F7N3O2 and molecular weight 421.27 g/mol, is a CATO reference standard with documented purity and traceability.
(2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide (C17H10F7N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H10F7N3O2 |
| Molecular Weight | 421.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related E Standards
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Recommended Standards
- Sodium 4-((4-(cyanoethynyl)benzoyl)oxy)-2,3,5,6-tetrafluorobenzenesulfonate (CAS 1644038-87-8)
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- 4-(tert-Butyl) 2-ethyl 6-iodo-4H-thieno[3,2-b]pyrrole-2,4-dicarboxylate (CAS 2820190-47-2)
- 2-((N-(2,4-dichloro-5-methoxyphenyl)-4-fluorophenyl)sulfonamido)-N-methylacetamide (CAS 338967-33-2)
- Dabigatran-13C-d3 (CAS CATO-C4X-108981)
- 3-((Phenylsulfonyl)methylene)oxetane (CAS 1221819-46-0)
- 6-Fluorochroman-2-carboxylic acid (CAS 99199-60-7)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(pyridin-4-yl)butanoic acid (CAS 270065-69-5)
- 59669-16-8 E775ICF82G Octanoic acid 1-C-13 UNII-E775ICF82G 1-13c-Caprylic acid (CAS 59669-16-8)
- N,2-Dimethyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-5-amine (CAS 1707568-82-8)
- 6-Chloro-2-methylquinolin-4-ol (CAS 15644-86-7)
- Ethyl 2-(2-(4-methoxyphenyl)thiazol-5-yl)acetate (CAS 885681-46-9)
- 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 24132-22-7)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
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