(3E)-3-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)-2,3-dihydro-1H-indol-2-one CAS 866131-60-4
| CAS No. | 866131-60-4 |
| Molecular Formula | C21H14ClN3OS |
| Molecular Weight | 391.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3E)-3-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)-2,3-dihydro-1H-indol-2-one is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (3E)-3-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)-2,3-dihydro-1H-indol-2-one (CAS 866131-60-4), a certified reference material (molecular formula C21H14ClN3OS, MW 391.87 g/mol) for analytical method development and quality control.
(3E)-3-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)-2,3-dihydro-1H-indol-2-one (C21H14ClN3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3E)-3-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)-2,3-dihydro-1H-indol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H14ClN3OS |
| Molecular Weight | 391.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Haloperidol Impurity 9 (CAS 148406-51-3)
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- 2-(Ethylsulfanyl)pyridine-4-carboxylic acid (CAS 1019485-25-6)
- 1-(Cyclopropylmethyl)-1H-pyrrolo[2,3-c]pyridin-7-ol (CAS 1340802-62-1)
- Torasemide Impurity 17 (CAS 5602-90-4)
- 4-(Thiophen-3-yl)butan-2-ol (CAS 1249111-13-4)
- 1-(4-(4-Fluorophenoxy)phenyl)ethan-1-amine (CAS 177842-45-4)
- Methyl 2-amino-4,6-bis(trifluoromethyl)benzoate (CAS 147494-42-6)
- Des-Lys20(Side Chain)-Semaglutide (CAS CATO-C4X-2226280)
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